Clene (NASDAQ: CLNN), Subsidiary Report Positive Clinical Results of CNM-Au8 Treatment

February 29, 2024 10:38:08

Clene (NASDAQ: CLNN), a late clinical-stage biopharmaceutical company, and its wholly owned subsidiary Clene Nanomedicine Inc., is reporting on the full clinical results for CNM-Au8(R), an investigational first-in-class therapy designed to improve central nervous system cells’ survival and function. Clene, which is focused on improving mitochondrial health and protecting neuronal function to treat neurodegenerative diseases, including amyotrophic lateral sclerosis (“ALS”) and multiple sclerosis (“MS”), presented the results at the ninth annual Americas Committee for Treatment and Research in Multiple Sclerosis Forum in Florida. The results were gathered from the VISIONARY-MS trial long-term open label extension (“LTE”) in participants with stable relapsing multiple sclerosis (“RMS”) totaling nearly three years of follow-up. According to the announcement, data gathered from the clinical trial indicate that long-term CNM-Au8 treatment results in “significant and clinically meaningful” improvement of vision and improvement of cognition. In addition, the company noted that treatment was well-tolerated, with no serious adverse events attributed to CNM-Au8 and no significant safety findings reported. The report noted that after completion of the double-blind period, 55 of 69 LTE-eligible study participants continued on CNM-Au8 30mg for up to an additional 96 weeks.

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About Clene Inc.

Clene and its wholly owned subsidiary, Clene Nanomedicine, is a late clinical-stage biopharmaceutical company focused on improving mitochondrial health and protecting neuronal function to treat neurodegenerative diseases, including amyotrophic lateral sclerosis, Parkinson’s disease and multiple sclerosis. CNM-Au8(R) is an investigational, first-in-class therapy that improves the survival and function of central nervous system cells via a mechanism that targets mitochondrial function and the NAD pathway while reducing oxidative stress. CNM-Au8 is a federally registered trademark of Clene Nanomedicine. The company is based in Salt Lake City, Utah, with R&D and manufacturing operations in Maryland. For more information, please visit www.Clene.com.

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