Archives: BioMedWire

November 2, 2020 12:12:57

Oncocyte (NYSE American: OCX), a molecular diagnostics company with a mission to provide actionable answers at critical decision points across the cancer care continuum, recently provided an update on DetermaRx’s global growth and adoption. According to the update, DetermaRx is a treatment stratification test that identifies stage I-IIA non-small cell lung cancer (“NSCLC”) patients at high risk of recurrence, despite ostensibly curative surgery, who may benefit from the addition of chemotherapy. Since its January commercial launch in the U.S., DetermaRx has begun to be reimbursed by Medicare and multiple private payers and has seen rapid adoption across 67 hospitals. “We are encouraged by the increasing quarter-over-quarter growth of DetermaRx,” Padma Sundar, head of commercial at Oncocyte, said in the press release. “Our rapid growth is taking place across all important metrics, such as test volume, reorder rate, inclusion in hospital ordering systems, and test adoption at premiere community practices as well as prestigious National Cancer Institute (“NCI”) designated cancer centers and National Comprehensive Network Cancer (“NCCN”) centers. We believe the rapid adoption of DetermaRx reflects the significant clinical need for this test, which is the only test currently available to drive critical treatment decisions for early-stage lung cancer patients who may be at risk for recurrence. Our compelling new prospective data demonstrates that treatment informed by DetermaRx significantly improves lung cancer patient survival, and we believe this test could be practice-changing, potentially guiding the use of not only chemotherapy but also the use of targeted therapies in the future.”

To view the full press release, visit https://ibn.fm/rfETQ

About Oncocyte Corporation

Oncocyte is a molecular diagnostics company whose mission is to provide actionable answers at critical decision points across the cancer care continuum. The company’s proprietary tests and pharmaceutical company services aim to save lives and improve outcomes by accelerating and optimizing the diagnosis and treatment of cancer. Oncocyte’s tests and services present multiple opportunities to advance cancer care while driving the growth of its revenue. The company recently launched DetermaRx(TM), a treatment stratification test to identify early-stage lung cancer patients who are at high risk for cancer recurrence post-resection, allowing them to be treated when their cancer may be more responsive to adjuvant chemotherapy. Oncocyte is also developing DetermaIO(TM), a gene expression test that identifies patients who are more likely to respond to checkpoint inhibitor immunotherapies. The company also plans to launch Therasure(TM)-CNI MONITOR, a blood-based immune therapy monitoring test. Oncocyte’s pharmaceutical company services help pharmaceutical companies to develop new cancer treatments, many of which may be linked to Oncocyte’s diagnostic tests. For more information about the company, visit www.Oncocyte.com.

About BioMedWire

BioMedWire (BMW) is an information service that provides (1) access to our news aggregation and syndication servers, (2) BioMedNewsBreaks that summarize corporate news and information, (3) enhanced press release services, (4) social media distribution and optimization services, and (5) a full array of corporate communication solutions. As a multifaceted financial news and content distribution company with an extensive team of contributing journalists and writers, BMW is uniquely positioned to best serve private and public companies that desire to reach a wide audience of investors, consumers, journalists and the general public. BMW has an ever-growing distribution network of more than 5,000 key syndication outlets across the country. By cutting through the overload of information in today’s market, BMW brings its clients unparalleled visibility, recognition and brand awareness. BMW is where news, content and information converge.

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BioMedNewsBreaks – AzurRx BioPharma Inc. (NASDAQ: AZRX) Secures $6.9M in Private Placement

November 2, 2020 11:52:39

AzurRx BioPharma (NASDAQ: AZRX), a company specializing in the development of non-systemic, recombinant therapies for gastrointestinal diseases, earlier this year announced the closing of a private placement financing (the “offering”). According to the update, AzurRx secured approximately $6.9 million in gross proceeds from certain accredited investors, with Alexander Capital LP acting as sole placement agent in the offering. The company intends to use net proceeds to eliminate short- and long-term indebtedness, as well as for general working capital purposes including product development. “We are very grateful for the continued support of our investors,” James Sapirstein, president and CEO of AzurRx said in the press release. “This financing allows us to achieve our short-term goals and continue the development of our MS1819 program for the treatment of exocrine pancreatic insufficiency in cystic fibrosis and chronic pancreatitis patients.”

To view the full press release, visit https://ibn.fm/db56x

About AzurRx BioPharma Inc.

AzurRx BioPharma is engaged in the research and development of non-systemic biologics for the treatment of patients with gastrointestinal disorders. MS1819-SD recombinant lipase for exocrine pancreatic insufficiency (“EPI”) is the company’s lead development program, and additional early stage research is being conducted for the prevention of hospital-acquired infections. The company is headquartered in Brooklyn, New York, with scientific operations based in Langlade, France. Additional information on the company can be found at www.AzurRx.com.

NOTE TO INVESTORS: The latest news and updates relating to AZRX are available in the company’s newsroom at https://ibn.fm/AZRX

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VistaGen Therapeutics Inc. (NASDAQ: VTGN) Preclinical Study Data Show Drug Combo’s Innovative Potential in Fight Against Major Depressive Disorder

November 2, 2020 11:39:50

Study results have exciting therapeutic potential across wide range of CNS indications.
VTGN focused on developing new generation of medications to treat anxiety, depression and more.
Company committed to finding treatment to help estimated 264 million people around the world who suffer from depression.

Noting that 17.3 million adults in the United States have had at least one major depressive episode and some 264 million people around the world suffer from depression, VistaGen Therapeutics (NASDAQ: VTGN) is committed to finding effective treatments for depression that reach beyond the current standard of care, which includes oral antidepressants and oral atypical antipsychotics. The company has released data from a second preclinical study of its oral investigational drug, AV-101, in combination with probenecid. The results, which complement findings from a prior preclinical study, indicate that AV-101, when combined with probenecid, substantially increased the brain concentration of its active metabolite, 7-Cl-KYNA, a potent and selective full antagonist of the N-methyl-D-aspartate receptor (NMDAr) glycine co-agonist site. The combination of drugs may therefore reduce rather than block NMDAr signaling—an effect which could carry significant therapeutic potential.

“These new positive results amplify our message that AV-101, when administered in combination with probenecid, has exciting therapeutic potential across a wide range of CNS (central nervous system) indications,” said VistaGen CEO Shawn Singh…

NOTE TO INVESTORS: The latest news and updates relating to VTGN are available in the company’s newsroom at https://ibn.fm/VTGN

About BioMedWire

BioMedWire (BMW) is a bio-med news and content distribution company that provides (1) access to a network of wire services via NetworkWire to reach all target markets, industries and demographics in the most effective manner possible, (2) article and editorial syndication to 5,000+ news outlets (3), enhanced press release services to ensure maximum impact, (4) social media distribution via the Investor Brand Network (IBN) to nearly 2 million followers, (5) a full array of corporate communications solutions, and (6) a total news coverage solution with BMW Prime. As a multifaceted organization with an extensive team of contributing journalists and writers, BMW is uniquely positioned to best serve private and public companies that desire to reach a wide audience of investors, consumers, journalists and the general public. By cutting through the overload of information in today’s market, BMW brings its clients unparalleled visibility, recognition and brand awareness. BMW is where news, content and information converge.

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CNS Pharmaceuticals (NASDAQ: CNSP) Announces Completion of Drug Manufacturing for Brain Cancer Trial

November 2, 2020 11:10:28

Houston-based CNS Pharmaceuticals is preparing to launch Phase 2 clinical testing of a novel brain cancer-fighting drug candidate called Berubicin early next year
The biopharmaceutical company recently announced that a U.S.-based company contracted to make Berubicin has completed its production process and an Italian company working on a dual track in Europe is expected to finish by the end of the year
Berubicin has shown promise in combatting Glioblastoma multiforme, an aggressive form of brain cancer commonly regarded as incurable. One participant in Berubicin’s Phase 1 trial remains cancer-free 14 years after the trial
CNS Pharmaceuticals, with its sublicensee partner WPD Pharmaceuticals, is also preparing for 2 clinical trials in Poland including the first Phase 1 pediatric trial of Berubicin and a parallel Phase 2 trial in adults

The U.S. manufacturer for a novel anthracycline being tested by biopharmaceutical company CNS Pharmaceuticals (NASDAQ: CNSP) as a potential new strategy in combatting an inexorable and ultimately fatal type of brain tumor has completed the manufacturing process for the drug candidate, known as Berubicin.

CNS Pharmaceutical engaged Pharmaceutics International, Inc. (“Pii”) to make Berubicin in the United States while BSP Pharmaceuticals S.p.A. (“BSP“) worked on a dual track to make Berubicin in Italy under the company’s strategy of supplying its upcoming Phase 2 trials with sufficient quantities of the…

NOTE TO INVESTORS: The latest news and updates relating to CNSP are available in the company’s newsroom at https://ibn.fm/CNSP

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Korean Researchers Develop Artificial Coating to Avert Bone Inflammation

November 2, 2020 11:05:51

Due to population aging, bone disease is becoming increasingly widespread. This trend has led to an increase in the use of orthopedic and dental implants to treat the condition. We can trace the history of implants all the way back to 1 AD, when wrought iron was fashioned into dental implants in ancient Rome. Despite the long history, various challenges are still linked to implant procedures, including inflammation or a loose implant stemming from slow fusing to the bone tissue.

To help mitigate these problems, an attempt has been made to coat implant materials with…

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Findings Suggest Link Between Deficiencies in Gut Microbes, Autism Spectrum Disorder

November 2, 2020 09:05:50

A group of researchers associated with various institutions in China has discovered a gut microbe deficiency in children who develop ASD (autism spectrum disorder). This is a developmental disability characterized by stereotyped and repetitive behavior and impaired social communication. In the research, which was published in the “Science Advances” journal, the team of researchers describes their study of gut microbes in autism spectrum disorder children and discusses their findings.

Previous research had suggested that issues with the gut microbiome may be the cause of…

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BioMedNewsBreaks – Oncocyte Corporation (NYSE American: OCX) Named Among the 2020 Best Places to Work in Orange County

October 30, 2020 12:52:04

Oncocyte (NYSE American: OCX), a molecular diagnostics company with a mission to provide actionable answers at critical decision points across the cancer care continuum, on Wednesday announced it has been named as one of the 2020 Best Places to Work in Orange County. Oncocyte ranked number four out of 40 in the medium-size company category. A project of the Orange County Business Journal and Best Companies Group, the awards program was created in 2009. “Great technologies and great strategies don’t do great things; great people accomplish great things,” said Ron Andrews, CEO of Oncocyte. “While our world of molecular diagnostics can be extremely technically oriented, having the right employees who can combine scientific brilliance with a heart for the patients we serve is essential to our success. We are blessed to have an incredibly talented, mission-oriented team who show up each day with humility and genuine care for one another. This combination is a foundational organizational attribute given the pace at which we expect everyone to work. We are very honored to be ranked in this year’s list given how young we are as a company here in Orange County and owe a big ‘thank you’ to our dedicated employees!”

To view the full press release, visit https://ibn.fm/4UT6r

About Oncocyte Corporation

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BioMedNewsBreaks – Genprex Inc. (NASDAQ: GNPX) Announces Launch of New Branding for Upcoming Combination Clinical Trials

October 30, 2020 11:26:33

Genprex (NASDAQ: GNPX), a clinical-stage gene therapy company developing potentially life-changing technologies for cancer and diabetes patients, today announced the launch of new branding for its upcoming oncology clinical trials. The trials combine Genprex’s lead drug candidate, REQORSA(TM) (quaratusugene ozeplasmid), with AstraZeneca’s Tagrisso(R) (osimertinib), which received U.S. Food and Drug Administration (“FDA”) Fast Track Designation earlier this year, as well as the combination of REQORSA with Merck’s Keytruda(R) (pembrolizumab), for the treatment of non-small cell lung cancer (“NSCLC”). “We are enthusiastically preparing for our upcoming clinical trials and are excited to launch the adoption of this branding,” said Rodney Varner, president and chief executive officer of Genprex. “We believe the Acclaim brand communicates our passion for providing hope to NSCLC patients for important new treatment options in the fight against this devastating disease and aligns us with the clinical, medical and patient communities.”

To view the full press release, visit https://ibn.fm/vunH1

About Genprex Inc.

Genprex is a clinical-stage gene therapy company developing potentially life-changing technologies for patients with cancer and diabetes. Genprex’s technologies are designed to administer disease-fighting genes to provide new treatment options for large patient populations with cancer and diabetes who currently have limited treatment options. Genprex works with world-class institutions and collaborators to in-license and develop drug candidates to further its pipeline of gene therapies in order to provide novel treatment approaches. The company’s lead product candidate, “GPX-001” (“quaratusugene ozeplasmid”), is being evaluated as a treatment for non-small cell lung cancer (“NSCLC”). GPX-001 has a multimodal mechanism of action that has been shown to interrupt cell signaling pathways that cause replication and proliferation of cancer cells; re-establish pathways for apoptosis, or programmed cell death, in cancer cells; and modulate the immune response against cancer cells. GPX-001 has also been shown to block mechanisms that create drug resistance. In January 2020, the U.S. Food and Drug Administration granted Fast Track Designation for GPX-001 for NSCLC in combination therapy with osimertinib (AstraZeneca’s “Tagrisso(R)”) for patients with “EFGR” mutations whose tumors progressed after treatment with osimertinib alone. For more information about the company, visit www.Genprex.com.

NOTE TO INVESTORS: The latest news and updates relating to GNPX are available in the company’s newsroom at http://ibn.fm/GNPX

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Researcher Develops App to Help Kidney, Heart Disease Patients Manage Diets

October 30, 2020 11:05:49

For many living with heart and kidney diseases, taking care of their health includes managing their diets to suit medical recommendations that restrict the consumption of some nutrients. While this might be easy for some, a majority find it hard to follow these recommendations without tracking their nutrition through the day.

To help with this, assistant professor and nephrologist Dr. Ibrahim Elali has created DecideDiet. This free…

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BioMedNewsBreaks – VistaGen Therapeutics (NASDAQ: VTGN) Featured in BioWorld Article

October 30, 2020 10:10:29

VistaGen Therapeutics (NASDAQ: VTGN), a biopharmaceutical company developing new generation medicines for anxiety, depression and other central nervous system (“CNS”) disorders, was featured in a recent BioWorld article titled, “CBC-funded Affamed merges with Everinsight, extends portfolio with Kissei PD candidate.” The publication discusses the merging of Affamed Therapeutics Ltd., an emerging biopharmaceutical company focused on opthamology markets in Greater China and funded by the large global venture capital firm, CBC Group, and EverInsight Therapeutics Inc., a biopharmaceutical company focused on central nervous system disorders and also funded by CBC Group. EverInsight and VistaGen entered into an exclusive development and commercialization agreement for VistaGen’s PH94B neuroactive nasal spray, a Phase 3-entering drug candidate for treatment of social anxiety disorder, earlier this year (https://ibn.fm/W6BOk). Under that agreement, VistaGen received a non-dilutive upfront payment of $5 million and, if Phase 3 development is successful, is eligible for up to $172 million in development and commercial milestone payment, plus royalties on commercial sales. According to the article, Affamed aims to bring in late-stage assets for China and other Asian markets focused on central nervous system and ophthalmology. As a result of the merger, VistaGen will work closely with the combined Affamed/EverInsight team on Phase 3 development and commercialization of PH94B in Greater China, South Korea and Southeast Asia. As noted in the article regarding the Affamed/EverInsight merger: “’In addition to bringing together complementary businesses, the combination strengthens the combined company’s global R&D capabilities,’ Affamed’s CEO Dayao Zhao told BioWorld. After the merger, Affamed now has a neurosteroid nasal spray, PH94B, which is moving into phase III development for social anxiety disorder with licensing rights from Vistagen Therapeutics Inc. in greater China, Korea and Southeast Asia.”

To view the full article, visit https://ibn.fm/ZkMnj

About VistaGen Therapeutics

VistaGen is a clinical-stage biopharmaceutical company developing new generation medicines for anxiety, depression and other CNS disorders where the current standard of care is inadequate, resulting in high unmet need. Each of VistaGen’s three drug candidates has a differentiated mechanism of action, an exceptional safety profile in all studies to date, and therapeutic potential in multiple CNS markets. For more information, please visit www.VistaGen.com.

NOTE TO INVESTORS: The latest news and updates relating to VTGN are available in the company’s newsroom at https://ibn.fm/VTGN

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COVID-19 Deals Chronic Disease Patients a Double Blow

October 30, 2020 09:05:42

A new study conducted by the University of New South Wales has discovered that right now is the most dangerous time for individuals with NCDs (noncommunicable diseases) such as cardiovascular conditions, respiratory problems, cancer and diabetes — primarily because of the COVID-19 pandemic.

The study found that individuals with NCDs were more likely…

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BioMedNewsBreaks – Genprex Inc. (NASDAQ: GNPX) Announces Conditional FDA Acceptance of Proprietary Name for Lead Drug Candidate

October 29, 2020 12:19:52

Genprex (NASDAQ: GNPX), a clinical-stage gene therapy company developing potentially life-changing technologies for patients with cancer and diabetes, has received conditional FDA acceptance of the proprietary name REQORSA(TM), its lead drug candidate for treatment of non-small cell lung cancer. The drug candidate was known previously by the laboratory designation GPX-001. The approval of the new name marks a critical branding milestone for the company. Genprex’s REQORSA (pronounced “re-KORE-suh”) immunogene therapy features the company’s exclusive ONCOPREX(TM) nanoparticle delivery system that delivers cancer-fighting genes. The name will be resubmitted to the FDA for final review and approval after all required clinical trials are completed; that final approval is based on the FDA’s approval of the product candidate. The new name was based on FDA’s guidelines for the submission and evaluation of proprietary names. Genprex selected the name based on a comprehensive review of name candidates, including a study of healthcare practitioners across the country to guarantee accurate prescription and safety interpretation of the name. “We are very pleased to receive FDA’s conditional acceptance of our proprietary name, REQORSA, which is a necessary step toward being able to market our lead drug candidate for non-small cell lung cancer,” said Genprex president and CEO Rodney Varner in the press release. “This name approval also marks an important milestone in our overall branding strategy, giving us a unique, easily understood name people can associate with the Genprex brand and mission.”

To view the full press release, visit https://ibn.fm/H3ph0

About Genprex Inc.

Genprex is a clinical-stage gene therapy company developing potentially life-changing technologies for patients with cancer and diabetes. Genprex’s technologies are designed to administer disease-fighting genes to provide new treatment options for large patient populations with cancer and diabetes who currently have limited treatment options. Genprex works with world-class institutions and collaborators to in-license and develop drug candidates to further its pipeline of gene therapies in order to provide novel treatment approaches. The company’s lead product candidate, GPX-001 (quaratusugene ozeplasmid), is being evaluated as a treatment for non-small cell lung cancer (“NSCLC”). GPX-001 has a multimodal mechanism of action that has been shown to interrupt cell signaling pathways that cause replication and proliferation of cancer cells; re-establish pathways for apoptosis, or programmed cell death, in cancer cells; and modulate the immune response against cancer cells. GPX-001 has also been shown to block mechanisms that create drug resistance. In January 2020, the U.S. Food and Drug Administration granted fast track designation for GPX-001 for NSCLC in combination therapy with osimertinib (AstraZeneca’s Tagrisso(R)) for patients with “EFGR” mutations whose tumors progressed after treatment with osimertinib alone. For more information, please visit the company’s website at www.Genprex.com

NOTE TO INVESTORS: The latest news and updates relating to GNPX are available in the company’s newsroom at http://ibn.fm/GNPX

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Approximately One-Third of US Young Adults Are Unaware of Common Signs of a Stroke

October 29, 2020 11:05:57

According to new research that was published in “Stroke,”, approximately 30% of adults below age 45 in the United States don’t know the five most common stroke symptoms. Strokes are the main cause of disability in the country as well as the fifth leading cause of death. Between 10% to 15% of the 795,000 individuals who suffer a stroke are young people, aged between 18 and 45, so recognizing the signs is vital. Other recent studies suggest that while stroke incidence is decreasing among the general population, its incidence and hospitalizations have grown by more than 40% in young people in the last few decades.

Khurram Nasir, the study’s author, stated that despite the medical community making significant strides…

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BioMedNewsBreaks – CNS Pharmaceuticals Inc. (NASDAQ: CNSP) Announces Completion of Drug for Clinical Trials

October 29, 2020 09:14:47

CNS Pharmaceuticals (NASDAQ: CNSP), a biopharmaceutical company specializing in the development of novel treatments for primary and metastatic cancers of the central nervous system, has through its European manufacturer, BSP Pharmaceuticals S.p.A. (“BSP”), finished manufacturing its lead drug candidate for upcoming Phase 2 clinical trials. Berubicin is CNSP’s lead drug candidate for the treatment of glioblastoma multiforme (“GBM”), an aggressive form of brain cancer that is incurable. With the completion of the manufacturing, CNS Pharmaceuticals is now ready to kick off its planned Phase 2 clinical trials and file an Investigational New Drug Application (“IND”). CNSP contracted with two manufacturers on two continents — BSP Pharmaceuticals S.p.A. and Pharmaceutics International Inc. (“Pii”) — to alleviate any potential risks. The decision also allowed the company to expand its supply chain and prepare for more convenient availability of Berubicin. Both BSP and Pii have completed manufacturing the drug. “We are pleased to continue to execute upon our dual-track drug product manufacturing strategy, as both our U.S. manufacturer, Pii, and European manufacturer, BSP, have now completed production of Berubicin Drug Product,” said CNS Pharmaceuticals CEO John Climaco in the press release. “The completion of the manufacturing process at both locations represents a key milestone for us and will further support our efforts to file an IND during the fourth quarter of this year. We are encouraged by our continued execution upon our pre-trial initiatives, and believe we remain positioned to initiate a U.S. Phase 2 trial for Berubicin during the first quarter of 2021.”

To view the full press release, visit https://ibn.fm/9Dyby

About CNS Pharmaceuticals Inc.

CNS Pharmaceuticals is developing novel treatments for primary and metastatic cancers of the brain and central nervous system. Its lead drug candidate, Berubicin, is proposed for the treatment of glioblastoma multiforme (“GBM”), an aggressive and incurable form of brain cancer. CNS holds a worldwide exclusive license to the Berubicin chemical compound and has acquired all data and know-how from Reata Pharmaceuticals Inc. related to a completed Phase 1 clinical trial with Berubicin in malignant brain tumors, which Reata conducted in 2006. In this trial, 44% of patients experienced a statistically significant improvement in clinical benefit. This 44% disease control rate was based on 11 patients (out of 25 evaluable patients) with stable disease, plus responders. One patient experienced a durable complete response and remains cancer-free as of February 20, 2020. These Phase 1 results represent a limited patient sample size and, while promising, are not a guarantee that similar results will be achieved in subsequent trials. By the end of 2020, CNS expects to commence a Phase 2 clinical trial of Berubicin for the treatment of GBM in the United States, while a sub-licensee partner undertakes a Phase 2 trial in adults and a first-ever Phase 1 trial in pediatric GBM patients in Poland. The company’s second drug candidate, WP1244, is a novel DNA binding agent that has shown in preclinical studies that it is 500 times more potent than the chemotherapeutic agent daunorubicin in inhibiting tumor cell proliferation. For more information about the company, please visit www.CNSPharma.com

NOTE TO INVESTORS: The latest news and updates relating to CNSP are available in the company’s newsroom at https://ibn.fm/CNSP

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Biomedical Engineer Invents Technique That May Help Improve Eyesight

October 29, 2020 09:05:00

A professor of biomedical engineering at the University of Miami College of Engineering, Noel Ziebarth, and her groundbreaking research may help in the development of treatments designed to help the blind see again. The professor is also head of the Biomedical Atomic Force Microscopy Lab where she uses scanning electron, atomic force and confocal microscopes to analyze the retina, cornea and lens of the human eye in its diseased and normal states.

Ziebarth is mainly interested in treatments that may be used to treat cataracts. Cataracts are…

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BioMedNewsBreaks – AzurRx BioPharma Inc. (NASDAQ: AZRX) Secures Financing to Fund Phase 2 Clinical Trials and Phase 3 Preparations

October 28, 2020

October 28, 2020 11:30:30

AzurRx BioPharma (NASDAQ: AZRX), a clinical-stage biopharmaceutical company, in July entered into a convertible preferred stock and warrant securities purchase agreement with certain accredited and institutional investors relating to the private placement of certain shares of convertible preferred stock and warrants for cash and in exchange for certain outstanding promissory notes as described in a recent update. In addition, the company entered into an exchange addendum to the purchase agreement with certain investors, relating to the exchange, as consideration in the private placement, of approximately $6.9 million aggregate in principal amount, plus all accrued and unpaid interest thereon, of its outstanding senior convertible promissory notes, originally due in Sept. 2020 (the “exchange”). “We are excited to have attracted the support of both new and existing investors for this financing, which funds our two Phase 2 clinical trials and Phase 3 preparations. In addition, the promissory note exchange furthers strengthens our balance sheet by removing $6.9 million in near-term debt obligations,” AzurRx CEO James Sapirstein said in the news release. “We thank the team at Alexander Capital for their continued support of the company and their dedication to making these transactions a success.”

To view the full press release, visit https://ibn.fm/2H5av

About AzurRx BioPharma Inc.

AzurRx BioPharma is a biopharmaceutical company specializing in the research and development of nonsystemic biologics for gastrointestinal disorders. The company is focused on the development of its lead drug candidate, MS1819. AzurRx is currently conducting two Phase 2 clinical trials of MS1819: the OPTION 2 monotherapy trial, and the Combination therapy trial, consisting of MS1819 in conjunction with porcine-derived pancreatic enzyme replacement therapy, the current standard of care. The company is headquartered in New York, NY, with scientific operations based in Langlade, France, and clinical operations in Hayward, California. For more information about the company, visit www.AzurRx.com.

NOTE TO INVESTORS: The latest news and updates relating to AZRX are available in the company’s newsroom at https://ibn.fm/AZRX

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Men More Likely to View Face Masks as Infringement on Freedom

October 28, 2020

October 28, 2020 11:05:11

According to new research that was published in the “Personality and Individual Differences” journal, both women and men are equally likely to wear face masks during the coronavirus pandemic. However, the study shows that women and men tend to have contrasting reasons for not wearing face masks.

Matt C. Howard, an assistant professor at the University of South Alabama, is a researcher involved in this study…

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Study Discovers Link Between Dopamine, Serotonin and Decision-Making

October 28, 2020

October 28, 2020 09:05:04

For the longest time, serotonin and dopamine have been linked to pleasure and reward. In a pioneer study done by researchers from University College London, findings published in “Neuron” show that these two neuromodulators may be connected to general cognition. This is essentially shaping how people view the world and act on those views.

Researchers simultaneously and continuously monitored serotonin and dopamine in human brains…

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BioMedNewsBreaks – AzurRx BioPharma Inc. (NASDAQ: AZRX) Announces Positive Results in Ongoing Phase 2 Combination Therapy Trial with MS1819

October 27, 2020 12:57:11

AzurRx BioPharma (NASDAQ: AZRX), a clinical-stage biopharmaceutical company, recently announced positive results from the first five patients in its Phase 2 combination therapy trial of MS1819 for the treatment of severe exocrine pancreatic insufficiency (“EPI”) in patients with cystic fibrosis (“CF”). In the primary efficacy analysis, patients receiving MS1819 in combination with PERT therapy achieved a clinically meaningful improvement in the coefficient of fat absorption (“CFA”) at each of the three dose levels. No adverse safety events were reported and, additionally, patients showed improvements in the key secondary endpoints, including body weight, stool consistency and reductions in the number of bowel movements and the incidence of steatorrhea. “We are thrilled to see such consistently positive responses from these initial patients in our ongoing Phase 2 combination therapy trial with MS1819. EPI is a very challenging disease with many CF patients unable to achieve healthy nutrition even when using the maximum number of allowed or tolerated PERT capsules, especially those in the moderate-severe categories,” AzurRx CEO James Sapirstein said of the results. “We look forward to completing treatment of all patients and announcing top line data in 2021.”

To view the full press release, visit https://ibn.fm/G4kBU

About AzurRx BioPharma Inc.

NOTE TO INVESTORS: The latest news and updates relating to AZRX are available in the company’s newsroom at https://ibn.fm/AZRX

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BioMedNewsBreaks – Predictive Oncology (NASDAQ: POAI) CEO Provides Company Updates on Exclusive NNW Audio Interview

October 27, 2020 11:34:25

Predictive Oncology (NASDAQ: POAI) CEO Carl Schwartz was featured in a recent NetworkNewsWire (“NNW”) audio interview. During the interview, Schwartz provided updates on the company’s subsidiaries, noted recent company milestones and outlined near-term goals. POAI, a knowledge-driven company focused on applying artificial intelligence (“AI”) to personalized medicine and drug discovery, has four wholly owned subsidiaries: Helomics, TumorGenesis, Skyline Medical and Soluble Biotech. Schwartz focused the discussion on these companies, offering brief insight into the operations of Skyline Medical and noting that the purpose of TumorGenesis was to develop a lab media to replace rats and mice in the scientific industries and in the testing of tumors, which the company has done. The next step, said Schwartz, is to get the kits out so people can use it, an effort that is “coming along handsomely.” In addition, Schwartz discussed Soluble Biotech, POAI’s newest subsidiary. Schwartz noted that the company is two labs “that we put together” and moved into a research park, quadrupling the working space. Schwartz explained that “the technology used by Soluble is proprietary. These machines . . . are the only machines of their kind. In the determination of solubility of products, they work wonders in that area.” Schwartz also discussed Helomics.

“The original basis of Helomics. . . was that physicians or hospitals would send their tumors to this company, and they would test the tumors with the known therapies of the day. . . . In that process, [Helomics] accumulated over 150,000 tumors covering over 137 different cancers. . . . That database is the largest of its kind in the world. . . .With that data, and the fact that we’ve sequenced these tumors, we have shown that we can provide quality information to anyone who needs it. There’s a lot going on at Helomics. We think we’ve validated the company. We’ve got assets that are one-of-a-kind in the world, and we think we are on our way to where we wanted to be when we first purchased this company a couple of years ago.”

To listen to the full interview, visit https://ibn.fm/xQQwT

To view the full press release, visit https://ibn.fm/MEFLq

About Predictive Oncology Inc.

Predictive Oncology operates through three segments (domestic, international and other), which contain four subsidiaries; Helomics, TumorGenesis, Skyline Medical and Soluble Biotech. Helomics applies artificial intelligence to its rich data gathered from patient tumors to both personalize cancer therapies for patients and drive the development of new targeted therapies in collaborations with pharmaceutical companies. TumorGenesis Inc. specializes in media that help cancer cells grow and retain their DNA/RNA and proteomic signatures, providing researchers with a tool to expand and study cancer cell types found in tumors of the blood and organ systems of all mammals, including humans. Skyline Medical markets its patented and FDA cleared STREAMWAY System, which automates the collection, measurement and disposal of waste fluid, including blood, irrigation fluid and others, within a medical facility, through both domestic and international divisions. Soluble Biotech is a provider of soluble and stable formulations for proteins including vaccines, antibodies, large and small proteins and protein complexes. For more information about the company, please visit www.Predictive-Oncology.com.

NOTE TO INVESTORS: The latest news and updates relating to POAI are available in the company’s newsroom at http://ibn.fm/POAI

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Strategic HCP Partnerships Virtual Summit Networking Hub for Healthcare Professionals

October 27, 2020 11:24:43

Virtual event set for Wednesday, Nov. 18–Friday, Nov. 20, 2020
Forum for healthcare professionals, executives of healthcare organizations and service providers
Three virtual environments — exhibit hall, session areas and network rooms — offer optimal opportunity for engagement
Hosted by Lincoln Health Network

The Strategic HCP Partnerships Summit — a virtual event this year — is shaping up to be a networking hub for healthcare professionals, executives of healthcare organizations (HCO) and service providers. The three-day event, scheduled for Nov. 18–20, 2020, offers a platform that promises to foster engagement and provide a wealth of opportunity to build and expand valuable business networks.

The event, one of a series of leading healthcare forums hosted by the Lincoln Health Network (LHN), also gives key decision-makers a chance to be apprised of current developments in the sector. LHN events have earned praise for their role in catalyzing innovation in the pharmaceutical, medical device and biotechnology fields, as well as facilitating collaboration across the…

For more information, please visit www.HCP.LincolnHealthNetwork.com

Comparison Between Saliva, Swab Coronavirus Tests

October 27, 2020 11:05:20

From the start of the pandemic, researchers and clinicians have been searching for nasopharyngeal swab alternatives. Tests administered using these swabs are hard to scale up for mass testing, they put health workers in closer contact with individuals who may be infected, and they require more supplies. Saliva has been suggested as an easy and low-cost alternative. However, its accuracy and efficacy remain a point of conflict.

Trials of saliva-based tests have been carried out in the field but produced mixed results. These results…

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BioMedNewsBreaks – Brain Scientific Inc. (BRSF) Announces Partnership with Dalmore Group for Upcoming Offering

October 27, 2020 10:52:55

Brain Scientific (OTCQB: BRSF), a neurology-focused medical device and software company, is partnering with the Dalmore Group, a member of the Financial Industry Regulatory Authority, Inc. (“FINRA”) and the Securities Investor Protection Corporation (“SIPC”), for a regulation A+ offering. Based in New York, the Dalmore Group has an active presence in the Reg A+ equity funding space and is one of the most active broker-dealers in the world for Regulation A+ offerings; the company has served as broker-dealer on more than 50 such offerings in the past year. Brain Scientific recently unveiled its exclusive NeuroCap(TM) device, a next-generation, 19-channel, hospital-grade disposable EEG headset. The new NeuroCap features Velcro materials for advanced adhesion during EEG testing. Studies indicate that more than 80% of patients hospitalized for COVID-19 are developing neurological symptoms. Consequently, Brain Scientific anticipates the new EEG cap will be used in a growing number of medical facilities across the United States. “We are delighted to get the Dalmore Group on board and to be able to offer our stock to a much wider pool of investors,” said Brain Scientific chairman Boris Goldstein in the press release. “Our partners are experienced with Regulation A+ offerings and are licensed in all 50 states. With our recent product development and new product launches, we feel the need to extend the proposed Regulation A+ Offering to attract additional investors, which we believe we can better accomplish by working with Dalmore.”

To view the full press release, visit https://ibn.fm/hVrNZ

About Brain Scientific Inc.

Brain Scientific is a commercial-stage healthcare company with two FDA-cleared products providing next-generation solutions to the neurology market. The company’s smart diagnostic devices and sensors simplify administration, shorten scan time and cut costs, allowing clinicians to make rapid decisions remotely and bridge the widening gap in access to neurological care. To learn more about the company, visit www.BrainScientific.com.

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Patent Suggests Apple Is Working on Smart Biomedical Glasses

October 27, 2020 09:05:45

It is commonly known that Apple is working on bettering its offerings in the wellness and health category. The company was recently awarded a patent that indicates that the firm is taking its approach into health a step further with a new invention: biomedical smart glasses.

Spotted by Patently Apple, the new patent describes this invention as a head-mounted display device that…

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BioMedNewsBreaks – Genprex Inc. (NASDAQ: GNPX) Appoints Eric Chapdelaine to Senior Manufacturing Team

October 26, 2020 11:55:19

Genprex (NASDAQ: GNPX), a clinical-stage gene therapy company developing potentially life-changing technologies for cancer and diabetes patients, today announced the promotion of Eric Chapdelaine to vice president of manufacturing. According to the update, Chapdelaine’s promotion is a result of the company’s achievement of key manufacturing milestones to support upcoming clinical trials of its lead drug candidate — GPX-001 (quaratusugene ozeplasmid). “The appointment of Eric to our senior team is a hallmark of our manufacturing achievements and highlights the progress we have made in scaling up our manufacturing to commercial scale, which will further supply our upcoming clinical trials,” said Michael Redman, Genprex’s executive vice president and chief operating officer.

To view the full press release, visit https://ibn.fm/7AUVc

About Genprex Inc.

NOTE TO INVESTORS: The latest news and updates relating to GNPX are available in the company’s newsroom at http://ibn.fm/GNPX

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Is It Acceptable for Police to Seize Your Biomedical Samples?

October 26, 2020 11:05:28

Let’s assume you’ve acquired a grant to begin a research study to investigate the spread of a certain disease in a population. So you gather your samples, do your research and publish your findings. Then out of nowhere, law enforcement shows up with a court order to obtain a sample from your collection that will help in the legal prosecution of one of the participants of your study.

As a researcher, would you find it unethical for the police…

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BioMedNewsBreaks – DarioHealth Corp. (NASDAQ: DRIO) Featured in Seeking Alpha Article Discussing Its Disruption in Chronic Disease Market

October 26, 2020 10:55:34

DarioHealth (NASDAQ: DRIO), a pioneer in the global digital-therapeutics market, was featured in a recent Seeking Alpha news article. The piece, titled “DarioHealth: Don’t Overlook This Mini Livongo,” discusses disruptors in the chronic disease market, such as Omada Health, Virta Health and Lark Health. The article specifically focuses on DRIO and the competition it brings to larger players like Livongo Health Inc. (NASDAQ: LVGO), which generated great returns for investors. The article reads, “After LVGO got bought out, I started to look for other digital health plays, specifically competitors to LVGO. Recently, I found a tiny company called DarioHealth (NASDAQ: DRIO) that had already increased 2-3x in the past few months. Despite this increase, however, I found that DRIO has substantial potential to appreciate even further, as I will discuss in this article.”

To view the full article, visit https://ibn.fm/x2x8S

About DarioHealth Corp.

DarioHealth is a leading, global digital-therapeutics company revolutionizing the way people with chronic conditions manage their health. By delivering evidence-based interventions driven by connected devices, data, high-quality software and coaching, the company makes the right thing to do the easy thing to do. The company’s cross-functional team operates at the intersection of life sciences, behavioral science, and software technology. Dario offers one of the highest-rated diabetes and hypertension solutions on the market. Its highly engaging, user-centric MyDario(TM) mobile app is used regularly by tens of thousands of consumers worldwide. DarioHealth is rapidly moving into new geographic markets to address chronic conditions using a performance-based approach to improve the health of users managing chronic disease. To learn more about the company and its digital health solutions, visit www.DarioHealth.com.

NOTE TO INVESTORS: The latest news and updates relating to DRIO are available in the company’s newsroom at http://ibn.fm/DRIO

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Study Discovers Global Distrust for COVID-19 Vaccines

October 26, 2020 09:05:43

A research team made up of researchers from the City University of New York Graduate School of Public Health and Health Policy (CUNY SPH) and other distinguished institutions such as the Barcelona Institute for Global Health and the Vaccine Confidence Project at the London School of Hygiene and Tropical Medicine announced yesterday that their research, which focused on potential global hesitancy to accept a coronavirus vaccine, was published in the “Nature Medicine” journal.

The researchers carried out their research based on previously collected COVID-SCORE…

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SPAC Merger Fires Boosters for 180 Life Sciences’ Exploration in Unmet Medical Needs of Anti-inflammatories Space

October 23, 2020 14:13:06

Biotechnology company 180 Life Sciences has launched a variety of advanced clinical and preclinical-stage efforts to develop novel anti-inflammatory treatments for patients with chronic illnesses
A planned merger with 180 Life Sciences advanced under a special purpose acquisition corporation (SPAC) is expected to be completed within the next month, resulting in a Nasdaq filing under the ticker ATNF
180 Life Sciences’s founders are an experienced team of medical scientists who pioneered anti-inflammatory pharmaceuticals in the 1990s that are still in use today, generating billions in revenue
The company’s own-IP clinical trials seek to resolve inflammation-related issues in conditions such as Dupuytren’s disease, frozen shoulder, arthritis, ulcerative colitis, liver fibrosis and nonalcoholic steatohepatitis
Analysts forecast the anti-inflammatory therapeutics market will be worth $191.42 billion by 2027, growing at a CAGR of 3 percent

Clinical stage biotechnology company 180 Life Sciences Corp., whose scientific teams are led by drug developers renowned for producing some of the largest-selling pharmaceuticals to ever come to market, is accelerating toward a planned Nasdaq launch under a special purpose acquisition corporation (“SPAC”) that expects to rocket its research into novel anti-inflammatory therapies toward some stellar goals.

KBL Merger Corp. (NASDAQ: KBLM, NASDAQ: KBLMR, and NASDAQ: KBLMW), previously announced its SPAC merger plans with 180 Life Sciences to create a company to be trading under the ticker…

NOTE TO INVESTORS: The latest news and updates relating to 180 Life Sciences are available in the company’s newsroom at http://ibn.fm/180

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CNS Pharmaceuticals, Inc. (NASDAQ: CNSP) Moves Closer to IND Filing as Manufacturing of Lead Drug Candidate Commences

October 23, 2020 12:12:15

Berubicin Expected to Commence Trials for the Treatment of Glioblastoma, An Aggressive Form of Brain Cancer Currently Considered Incurable
Production of Berubicin Begins in the U.S. and Europe
Dual Manufacturing Facilities Engaged to Reduce Supply Chain Interruptions
IND for Berubicin Could Be Filed by Year End

CNS Pharmaceuticals, Inc. (NASDAQ: CNSP) expects to have an Investigational New Drug Application (“IND”) ready for its lead drug candidate, Berubicin, by the end of 2020. An approved IND would give the biotech company, which is developing treatments for primary and metastatic cancers of the brain and central nervous system, the green light to go ahead with clinical trials. In June, CNS Pharmaceuticals signed agreements with two manufacturing entities—one in the U.S., the other in Italy—for the production of Berubicin. Three months later, the manufacturing process has commenced, taking the company a step closer to getting an IND approved by the Food and Drug Administration (“FDA”). Berubicin has been specifically developed to target cancers of the brain, including the first targeted indication of glioblastoma multiforme (“GBM”), an aggressive form of brain cancer currently considered incurable. To increase awareness of this destructive disease, a segment on “The Balancing Act, Behind the Mystery,” which airs on Lifetime TV, is focused on glioblastoma. The segment can be viewed here: (click for link).

The manufacturing of Berubicin marks an important milestone on the way to initiating clinical studies on GBM patients. CNS Pharmaceuticals has already completed synthesis of the Berubicin Active Pharmaceutical Ingredient (“API”), which has been shipped to Pii and BSP, manufacturing entities that will prepare an injectable form of Berubicin ready for…

NOTE TO INVESTORS: The latest news and updates relating to CNSP are available in the company’s newsroom at https://ibn.fm/CNSP

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BioMedNewsBreaks – KBL Merger Corp. IV’s (NASDAQ: KBLM) Special Meeting to be Held November 5, 2020, 180 Life Sciences Featured in Exclusive Broadcast

October 23, 2020 11:09:43

KBL Merger Corp. (NASDAQ, KBLMKBL, KBLMR, KBLMW) (“KBL”), a special purpose acquisition company (“SPAC”) that previously announced the agreement to acquire 180 Life Sciences Corp., today announced postponement of the special meeting of its stockholders (the “Special Meeting”) to November 5, 2020. KBL determined to postpone the Special Meeting (originally scheduled for Monday, October 26, 2020) so that it better aligns with anticipated timing of the proposed business combination with 180 Life Sciences. As a result of this change, the Special Meeting will now be held at 10:00 a.m., local time, on November 5, 2020, at the offices of KBL located at 30 Park Place, Suite 64B, New York, NY 10007. Also as a result of this change, the date and time by which stockholders seeking to exercise redemption rights must tender their public shares physically or electronically and submit a request in writing that KBL redeem their public shares for cash to KBL’s transfer agent, Continental Stock Transfer & Trust Company, is being extended to 5:00 p.m. Eastern Time on November 3, 2020.

In addition, 180 Life Sciences today announced the availability of a broadcast titled “Banking on the Next Blockbuster Drug.” The broadcast covers the company’s placement in an editorial published by NetworkNewsWire (“NNW”), one of 50+ brands in the InvestorBrandNetwork (“IBN”), a multifaceted financial news and publishing company for private and public entities. The piece discusses enormous amounts of time and money that pharmaceutical companies invest into the research and development of new drugs, and rare occasions when these are approved and generate more than $1 billion per year in sales, a benchmark in the industry commonly called a “blockbuster.” The piece discusses 180 Life Sciences team’s significant expertise in developing new therapeutics that were sold to big pharma for billions. Renowned for development of some of the largest-selling drugs to ever come to market, the team aims to “do it again with a pipeline of drug candidates in sequential stages of development that address large untapped markets. The founding scientists at 180 Life Sciences discovered the anti-TNF drug class that led to Remicade, the fourth all-time best-selling drug in the world.”

To view the full press release and listen to the podcast, visit https://ibn.fm/OXrin and https://ibn.fm/OtXNT

About KBL Merger Corp. IV

KBL Merger Corp. is a blank check company that raised $115 million with the goal of identifying and acquiring a company with a strong value proposition mainly in the U.S. health care industry. KBL Merger Corp. focused on this industry due to its management’s deep experience in this large, growing segment of the U.S. economy. Marlene Krauss, MD is the CEO of KBL Merger Corp. This is Dr. Krauss’ fourth SPAC in the healthcare space. She has invested more than $1 billion through three institutional venture capital funds, numerous IPOs and three prior SPACS. For more information, visit www.KBLMerger.com.

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Social Distancing, Masks May Not Be Enough to Prevent Coronavirus Infection

October 23, 2020 11:05:53

When the pandemic began, many countries introduced guidelines to help curb the spread of the coronavirus. The most common of these included:

1. Social distancing

2. Avoiding crowds; limiting the number of people in public places

3. Wearing a mask in public

However, these recommendations are based on…

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Research Unveils Potential Link Between Blood Groups and Coronavirus Susceptibility

October 23, 2020 09:05:15

Last week, “Blood Advances” published two studies that suggest people with O blood type may be at a lower risk of contracting COVID-19. In addition, when these individuals do get sick, studies suggest that they have a reduced likelihood of experiencing organ complications or other serious outcomes.

With the ongoing pandemic, the biomedical research community is working diligently to identify potential therapeutic targets and coronavirus risk factors…

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Pioneer Study Discovers Link Between Lowered Neuroplasticity and Obesity

October 22, 2020

October 22, 2020 11:05:00

A pioneer study carried out by researchers from the University of South Australia discovered that individuals who are severely overweight are less likely to be able to create new neural pathways and re-wire their brains. This discovery will have significant implications for people who are recovering from brain injuries or a stroke.

The paper, written by researchers from Deakin University and University of South Australia, was published in “Brain Sciences.” The research showed…

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New Study Suggests That Sitting May Be Good for Your Mind

October 22, 2020

October 22, 2020 09:05:09

We’ve probably heard this at least once in our lives, how adults of all ages should move more as well as engage in regular exercise and sit less. This has been said to make people feel better and also reduce the risk of chronic diseases.

However, a new study on brain and cognition from Colorado State University that involved older adults suggests that some degree of a sedentary lifestyle isn’t so bad after all…

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Did You Know Fats Fight Against Pathogens in Your Body?

October 21, 2020 11:05:21

Researchers from University of Queensland recently discovered that the droplets of fat that exist inside our cells help our body’s defense system fight back against infections.

The international collaboration between researchers Professor Albert Pol from the University of Barcelona and Professor Robert Parton from UQ Institute for Molecular Bioscience…

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BioMedNewsBreaks – 180 Life Sciences Corp. Featured in NNW Editorial Discussing Big Pharma Acquisitions

October 21, 2020 10:53:00

180 Life Sciences Corp. was discussed prominently in an editorial published by NetworkNewsWire (“NNW”), one of 50-plus brands in the InvestorBrandNetwork (“IBN”). The editorial, titled “Banking on the Next Blockbuster Drug,” discusses the significant amounts of time and money being invested by big pharma companies in the pursuit of new drugs, especially those that offer the potential to become blockbuster drugs. A blockbuster drug, or one that generates more than $1 billion in annual sales, can provide enormous benefits for the company that owns and manufactures it. Therefore, large companies operating in the pharmaceutical space commonly acquire promising new drugs — and the companies that are developing those drugs. 180 Life Sciences is one of those companies. 180 Life Sciences Corp. was founded by four scientists that have a successful track record of developing new therapeutics that were acquired by larger pharmaceutical companies, sometimes for billions of dollars. The group of renowned scientist-entrepreneurs is focusing on replicating their past success with a pipeline of drug candidates in sequential stages of development that target untapped markets with significant potential.

To view the full press release, visit https://ibn.fm/J32iu

About 180 Life Sciences Corp.

180 Life Sciences is a clinical-stage biotechnology company focused on the development of novel drugs that fulfill unmet needs in inflammatory diseases, fibrosis and pain by leveraging the combined expertise of luminaries in therapeutics from Oxford University, the Hebrew University and Stanford University. KBL Merger Corp. IV previously announced plans to merge with 180 Life Sciences and, in connection with the merger, consummated a bridge financing on June 29, 2020, and submitted its latest S4 filing with the SEC on Aug. 28, 2020. Close of the business combination is expected in the fourth quarter of 2020. Following the merger, the new company will be listed on the Nasdaq Capital Market under ticker symbol “ATNF.” For more information, visit the company’s website at www.180LifeSciences.com.

KBLM has valued 180 Life Sciences at $175 million, with the acquisition being carried out via a share swap, with each share of 180 Life Sciences to be exchanged for one share of KBLM.

NOTE TO INVESTORS: The latest news and updates relating to 180 Life Sciences are available in the company’s newsroom at http://ibn.fm/180

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BioMedNewsBreaks – AzurRx BioPharma Inc. (NASDAQ: AZRX) Forms New Scientific Advisory Board

October 21, 2020 09:57:36

AzurRx BioPharma (NASDAQ: AZRX), a clinical-stage biopharmaceutical company focused on developing treatments for gastrointestinal diseases using recombinant proteins, has announced the formation of a Scientific Advisory Board (“SAB”) designed to provide the company with invaluable expertise and insights. The company also announced that three leading global experts in exocrine pancreatic insufficiency (“EPI”) in patients with cystic fibrosis and chronic pancreatitis have been appointed to the board: Michael Konstan, MD; Darwin L. Conwell, MD; and Michael Wilschanski, MD. Konstan is vice dean for translational research and the Gertrude Lee Chandler Tucker Professor of Pediatrics at Case Western Reserve University School of Medicine; he is also the Austin Ricci chair in pediatric pulmonary care and research at University Hospitals Rainbow Babies and Children’s Hospital in Cleveland, Ohio. Konstan has spent his entire professional career in the care and research of people with cystic fibrosis (“CF”). Conwell is a gastroenterology physician-scientist specializing in pancreas disorders and is a professor of medicine at The Ohio State University College of Medicine where he serves as director of the Division of Gastroenterology, Hepatology and Nutrition at The Ohio State Wexner Medical Center. He is an NIH-funded physician-scientist with over 200 peer reviewed publications. The leader of numerous national and international studies of potentially new therapies in CF, Wilschanski is director of pediatric gastroenterology at Hadassah Hebrew University Medical Center. In addition, he also serves as the director of the Electrophysiology Laboratory in Hadassah where he performs in vivo and in vitro measurements of electrolyte transport, which is used diagnostically and therapeutically in CF. “We are thrilled to have this distinguished group of scientific leaders helping to guide our research and clinical development efforts as we advance our MS1819 program for the treatment of exocrine pancreatic insufficiency associated with cystic fibrosis and chronic pancreatitis patients,” said AzurRx CEO James Sapirstein in the press release.

To view the full press release, visit https://ibn.fm/10o6A

About AzurRx BioPharma Inc.

NOTE TO INVESTORS: The latest news and updates relating to AZRX are available in the company’s newsroom at https://ibn.fm/AZRX

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Coronavirus Lockdowns Forestalled Thousands of Air Pollution-Related Fatalities, New Study Finds

October 21, 2020 09:05:54

A new study reveals that the lockdowns imposed in various countries to curb the spread of COVID-19 at the beginning of the pandemic around Europe and in China improved air quality. This was seen in regions that suffered from high mortality rates caused by air pollution.

Scientists from the University of Notre Dame recently published research in the Lancet Planetary Health journal that showed the decline in particulate matter concentrations…

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Predictive Oncology Inc. (NASDAQ: POAI) Industry Leader in Growing Precision Medicine Market

October 21, 2020 08:38:51

Recent study reports CAGR of 9.7% in precision medicine space.
Predictive Oncology focused on use of data, artificial intelligence to develop personalized cancer therapies.
One of POAI’s primary projects is building multi-omic predictive models of tumor drug response

A recent study of the global precision medicine market indicates a bright future for the industry, especially for U.S.-based companies focusing on cancer research, such as Predictive Oncology Inc. (NASDAQ: POAI). The study reported a CAGR of 9.7% in the sector, with North America dominating the market and oncology expected to hold the highest market.

“Precision medicine, a combination of molecular biology techniques and systems biology, is an emerging approach for disease treatment and prevention,” the Mordor Intelligence study stated…

NOTE TO INVESTORS: The latest news and updates relating to POAI are available in the company’s newsroom at http://ibn.fm/POAI

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Loss of Interest May Be a Sign of Dementia

October 20, 2020

October 20, 2020 11:05:37

According to a study that was published in the online issue of Neurology on October 14, older adults who show no interest in normal activities or have severe apathy have a larger chance of developing dementia as compared to people with fewer apathy symptoms.

Meredith Bock, from the University of California and the author of the study says that apathy is distressing to family members, especially when people do not want to meet up with friends or family or they are no longer interested in what they used to like…

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BioMedNewsBreaks – CNS Pharmaceuticals Inc. (NASDAQ: CNSP) Announces Completion of Manufacturing of Lead Drug Candidate

October 20, 2020

October 20, 2020 09:11:45

CNS Pharmaceuticals (NASDAQ: CNSP), a biopharmaceutical company specializing in the development of novel treatments for primary and metastatic cancers of the central nervous system, has completed the manufacturing process for Berubicin Drug Product. CNSP’s U.S. manufacturer, Pharmaceutics International Inc. (“Pii”), has finished manufacturing the drug, which is the company’s lead drug candidate for the treatment of glioblastoma multiforme (“GBM”), an aggressive form of incurable brain cancer. In an attempt to diversify its supply chain, provide for local accessibility of Berubicin and reduce COVID-19-related delay risks, CNS had implemented a dual-track drug product manufacturing approach that used two different manufacturers for the drug; the two companies are located in different countries. CNSP contracted with Pii to make the drug in the United States and is working with BSP Pharmaceuticals S.p.A. (“BSP”) in Italy as well. BSP is on schedule to complete manufacturing later this year. CNS has also partnered with three separate companies as it prepares for its upcoming clinical trial of Berubicin. Worldwide Clinical Trials is the project’s contract research organization, Image Analysis Group (“IAG”) is the imaging partner and Berry Consultants will be the biostatistical advisor for the Phase 2 trial design. “Completing the manufacturing process for Berubicin in the United States is an essential step in our preparations to file an IND during the fourth quarter of this year,” CNS Pharmaceuticals CEO John Climaco stated in the press release. “We are extremely pleased to achieve yet another milestone in our preparation efforts and demonstrate our continued ability to execute upon both our operational and clinical strategies in a timely and proficient manner. We remain committed to further progressing our trial preparations, as we look forward to initiating a U.S. Phase 2 trial for Berubicin during the first quarter of 2021.”

To view the full press release, visit https://ibn.fm/nyxZv

About CNS Pharmaceuticals Inc.

CNS Pharmaceuticals is developing novel treatments for primary and metastatic cancers of the brain and central nervous system. Its lead drug candidate, Berubicin, is proposed for the treatment of glioblastoma multiforme (“GBM”), an aggressive and incurable form of brain cancer. CNS holds a worldwide exclusive license to the Berubicin chemical compound and has acquired all data and know-how from Reata Pharmaceuticals Inc. related to a completed Phase 1 clinical trial with Berubicin in malignant brain tumors, which Reata conducted in 2006. In this trial, 44% of patients experienced a statistically significant improvement in clinical benefit. This 44% disease control rate was based on 11 patients (out of 25 evaluable patients) with stable disease, plus responders. One patient experienced a durable complete response and remains cancer-free as of February 20, 2020. These Phase 1 results represent a limited patient sample size and, while promising, are not a guarantee that similar results will be achieved in subsequent trials. By the end of 2020, CNS expects to commence a Phase 2 clinical trial of Berubicin for the treatment of GBM in the U.S., while a sub-licensee partner undertakes a Phase 2 trial in adults and a first-ever Phase 1 trial in pediatric GBM patients in Poland. The company’s second drug candidate, WP1244, is a novel DNA binding agent that has shown in preclinical studies that it is 500 times more potent than the chemotherapeutic agent daunorubicin in inhibiting tumor cell proliferation. For more information about the company, visit www.CNSPharma.com

NOTE TO INVESTORS: The latest news and updates relating to CNSP are available in the company’s newsroom at https://ibn.fm/CNSP

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Researchers Develop Portable Device for Testing Cancer Biomarkers

October 20, 2020

October 20, 2020 09:05:44

Researchers at Brock and McMaster universities have developed a prototype for a tool which will allow patients to use a blood sample to test for the presence of cancer biomarkers. This technology has specifically been designed to assess the levels of prostate-specific antigens (“PSA”), but it can be tweaked to test for other cancers as well.

According to the researchers, the device operates in just the same way that hand-held glucose monitors work…

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BioMedNewsBreaks – Why CNS Pharmaceuticals Inc. (NASDAQ: CNSP) Is ‘One to Watch’

October 19, 2020

October 19, 2020 11:29:20

CNS Pharmaceuticals (NASDAQ: CNSP) is a biopharmaceutical company specializing in the development of novel treatments for primary and metastatic cancers of the brain and central nervous system. A recent article discussing CNS Pharmaceuticals reads, “The company’s lead drug candidate, Berubicin, is proposed for the treatment of glioblastoma multiforme (“GBM”), an aggressive and incurable form of brain cancer. Berubicin also has potential to treat other central nervous system malignancies. Based on limited clinical data, Berubicin appears to be the first anthracycline to cross the blood brain barrier in the adult brain, and it was the subject of a successful Phase 1 study which found the MDT and produced efficacy data as well.”

To view the full article, visit https://ibn.fm/zuyCE

About CNS Pharmaceuticals Inc.

CNS Pharmaceuticals is developing novel treatments for primary and metastatic cancers of the brain and central nervous system. Its lead drug candidate, Berubicin, is proposed for the treatment of glioblastoma multiforme (“GBM”), an aggressive and incurable form of brain cancer. CNS holds a worldwide exclusive license to the Berubicin chemical compound and has acquired all data and know-how from Reata Pharmaceuticals Inc. related to a completed Phase 1 clinical trial with Berubicin in malignant brain tumors, which Reata conducted in 2006. In this trial, 44% of patients experienced a statistically significant improvement in clinical benefit. This 44% disease control rate was based on 11 patients (out of 25 evaluable patients) with stable disease, plus responders. One patient experienced a durable complete response and remains cancer-free as of February 20, 2020. These Phase 1 results represent a limited patient sample size and, while promising, are not a guarantee that similar results will be achieved in subsequent trials. By the end of 2020, CNS expects to commence a Phase 2 clinical trial of Berubicin for the treatment of GBM in the United States, while a sub-licensee partner undertakes a Phase 2 trial in adults and a first-ever Phase 1 trial in pediatric GBM patients in Poland. The company’s second drug candidate, WP1244, is a novel DNA binding agent that has shown in preclinical studies to be 500 times more potent than the chemotherapeutic agent daunorubicin in inhibiting tumor cell proliferation. For more information, visit the company’s website at www.CNSPharma.com.

NOTE TO INVESTORS: The latest news and updates relating to CNSP are available in the company’s newsroom at https://ibn.fm/CNSP

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The Body’s Endocannabinoids Can Fight Intestinal Infections

October 19, 2020

October 19, 2020 11:05:06

A study led by researchers at the University of Texas Southwestern Medical Center suggests that native chemicals (endocannabinoids), which are similar to the cannabinoids produced by marijuana plants, have the potential to inhibit the virulence of intestinal bacteria.

The team found that our endocannabinoids can shut down the genes which are required for some intestinal pathogens to colonize and cause disease….

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Electromagnetic Fields Show Potential in Treating Diabetes in Animal Models

October 19, 2020

October 19, 2020 09:05:12

Researchers seem to have discovered a new way to manage diabetes without using needles or any other invasive means. The University of Iowa team found that when diabetic mice were exposed to a combination of magnetic fields and static electricity fields for a few hours on a daily basis, it caused them to have normal insulin and blood sugar levels. This unexpected discovery opens the door to a novel way of managing diabetes in humans more easily and safely.

According to the findings which appeared in the journal Cell Metabolism on October 6, the initial discovery which led to this research was purely accidental…

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4 Factors Behind the Rapid Spread of COVID-19 in the US

October 16, 2020

October 16, 2020 14:08:09

A lot can be said about what should or shouldn’t have been done to stem the spread of the novel coronavirus across the U.S. at the beginning of this year, but the truth is that the U.S. has unique factors that have influenced the trajectory of this pandemic. We analyze some of those crucial driving factors.

A Large Population

The U.S. is undeniably the third most populous country in the world, and that huge population provides a large sample space for the virus to get willing or unwilling hosts. When global COVID-19 cases are analyzed, the most affected countries also double as those with the largest populations. For example, the U.S., Russia, India, Brazil and Mexico. China doesn’t qualify…

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How to Fix Continued Medical Supply Shortages

October 16, 2020

October 16, 2020 11:00:39

It is hard to believe that the medical supply shortages which manifested a few weeks into the COVID-19 pandemic persist and have gotten worse in some cases. Ventilators, PPE and testing reagents are just a few of the critically needed medical supplies that the U.S. appears to be unable to get hold of in sufficient quantities. But why is this so?

In 2004, the administration of the day created the Strategic National Stockpile (“SNS”) with the aim of having a safety net during short-term emergencies, such as terrorist attacks. While this entity wasn’t designed or even equipped to handle an emergency of the scale of this current pandemic, they nevertheless should have been in position to alleviate…

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180 Life Sciences Corp. Expands IP Portfolio with EU, U.S., and Chinese Patents

October 16, 2020

October 16, 2020 10:00:37

The company’s patent portfolio includes its own intellectual property and exclusive worldwide licenses, including in the U.S., Canada, Europe, Australia, Hong Kong, and China
180 Life Sciences is in the final stages of its merger process with KBL Merger Corp. IV, with the resulting entity to list on NASDAQ under the ticker “ATNF”
The company is devoting its clinical-stage biotechnology research to producing solutions that will help battle inflammation. Its primary focus is to treat fibrosis and inflammation using anti-TNF therapy
The estimated annual market size for anti-inflammatory therapeutics is projected to grow to an estimated $106.1 billion in 2020.

KBL Merger Corp. IV (NASDAQ: KBLM), a special purpose acquisition corporation (“SPAC”) that has signed a detailed merger agreement with 180 Life Sciences Corp., announced that the company has continued to expand its IP portfolio. 180 Life Sciences Corp. is a clinical-stage biotech company currently in the developmental stage of three novel drugs. These drugs will fulfill the unmet need within the healthcare industry for inflammatory diseases, pain, and fibrosis.

The current patent portfolio that 180 Life Sciences Corp. has applied and received licenses for covers 14 patent families consisting of 42 patents issued and 32 pending in jurisdictions such as the United States, Europe, Canada, Japan, Australia, and…

NOTE TO INVESTORS: The latest news and updates relating to 180 Life Sciences are available in the company’s newsroom at http://ibn.fm/180

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Can China Deliver the COVID-19 Vaccine as Promised?

October 15, 2020 14:33:46

China is currently conducting COVID-19 vaccine trials in a number of countries which include Argentina, Peru and the United Arab Emirates. While China’s four out of the current dozen global vaccine candidates undergoing clinical trials haven’t been proved to be safe or even effective, the country has promised to avail millions of vaccine doses to several countries, including those in which the trials are being conducted and a host of low income countries with which it shares cordial relationships.

As China makes those bold promises, questions remain regarding its capacity to supply all those vaccine doses, and even whether the international community through the World Health Organization and other entities will approve those vaccines for use. We explore some of those issues in this analysis…

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BioMedNewsBreaks – Predictive Oncology Inc.’s (NASDAQ: POAI) Soluble Biotech Looks to Bright Future with First Contract on the Books

October 15, 2020 13:00:12

Predictive Oncology (NASDAQ: POAI)’s Soluble Biotech division has finalized its first substantial contract with a pharmaceutical company since its acquisition by POAI earlier this year (https://ibn.fm/gXjd2). Soluble Biotech is a provider of stable and soluble formulations for proteins including vaccines, antibodies, large and small proteins and protein complexes. Under the contract, Soluble Biotech will provide its expertise in protein expression and solubility studies. A recent article discussing this quotes Soluble Biotech founder Dr. Larry DeLucas. “Our first contract is a major milestone and validates our recent move into a new, larger facility,” Dr. DeLucas stated. “We quadrupled our laboratory and office space, some of which will eventually include a GMP facility. Additionally, we acquired state-of-the-art equipment to support our fermentation, therapeutic protein formulation development and protein stability studies. With our first contract on the books, and expanded capacity, the future is bright. We are currently negotiating several additional contracts with biotechnology and pharmaceutical companies.”

To view the full article, visit https://ibn.fm/iO8WW

About Predictive Oncology Inc.

Predictive Oncology operates through three segments (domestic, international and other), which contain four subsidiaries; Helomics, TumorGenesis, Skyline Medical and Skyline Europe. Helomics applies artificial intelligence to its rich data gathered from patient tumors to both personalize cancer therapies for patients and drive the development of new targeted therapies in collaborations with pharmaceutical companies. Helomics’ CLIA-certified lab provides clinical testing that assists oncologists in individualizing patient treatment decisions by providing an evidence-based road map for therapy. In addition to its proprietary precision oncology platform, Helomics offers boutique CRO services that leverage its TruTumor(TM), patient-derived tumor models coupled to a wide range of multi-omics assays (genomics, proteomics and biochemical), and an AI-powered proprietary bioinformatics platform to provide a tailored solution to its clients’ specific needs. Predictive Oncology’s Skyline Medical division markets its patented and FDA-cleared STREAMWAY System, which automates the collection, measurement and disposal of waste fluid, including blood, irrigation fluid and others, within a medical facility, through both domestic and international divisions. The company has achieved sales in five of the seven continents through both direct sales and distributor partners. For more information, please visit www.Predictive-Oncology.com.

NOTE TO INVESTORS: The latest news and updates relating to POAI are available in the company’s newsroom at http://ibn.fm/POAI

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AzurRx BioPharma Inc. (NASDAQ: AZRX) is “One to Watch”

October 15, 2020 11:36:30

AzurRx BioPharma’s lead therapeutic, MS1819, is a recombinant lipase treatment for exocrine pancreatic insufficiency and is currently targeting patients with cystic fibrosis and chronic pancreatitis – an established global market of more than $2 billion
The company is currently pursuing parallel monotherapy and combination therapy trials, which are anticipated to produce topline data in Q1 2021 and Q2 2021, respectively
Previously completed clinical trials of MS1819 showed primary and secondary endpoint efficacy, with a positive safety profile
To fully finance its ongoing Phase 2 trials and being preparations for a pivotal Phase 3 study in 2021, as well as to fund current operations, the company raised gross cash capital of $22.1 million as of July 2020
AzurRx is determined to develop MS1819 as a safer alternative to porcine pancreatic enzyme replacement therapy, significantly reducing the pill burden of cystic fibrosis patients

AzurRx BioPharma (NASDAQ: AZRX) is a clinical-stage biopharmaceutical company focused on developing treatments for gastrointestinal diseases using recombinant proteins.

The company’s lead drug candidate is MS1819, a recombinant lipase for the treatment of exocrine pancreatic insufficiency (“EPI”) in patients suffering from cystic fibrosis and…

NOTE TO INVESTORS: The latest news and updates relating to AZRX are available in the company’s newsroom at https://ibn.fm/AZRX

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Why Depression Often Makes You Feel Tired

October 15, 2020 11:02:36

People who suffer from depression usually report that they feel so fatigued that even mundane tasks, such as leaving their beds, are very difficult to manage. According to research, approximately 90% of all the people with major depressive disorder suffer from fatigue. Here are some of the reasons why you may feel fatigued if you suffer from depression.

Sleep Problems

Sleep is essential because it allows the body to replenish its energy supplies and to recover from any damage sustained during the waking hours. If you are depressed, you are likely to have difficulties falling asleep or even staying asleep. This sleep deprivation means that your energy reserves…

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Swedish Research Shows Unmarried Males are More Likely to Die of COVID-19

October 14, 2020 13:47:55

Being a man, not being married, and having a low income are some of the factors which new research has shown can increase your risk of dying from COVID-19. This research was conducted by a team at Stockholm University in Sweden and the findings were published in the journal Nature Communications.

The research team combed through the data available at the Swedish National Board for Health and Welfare on the known COVID-19 fatalities in the country. The researchers were specifically interested in the deaths of people aged 20 or older. The statistics studied were from the onset…

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180 Life Sciences Corp. Bringing Hope to Those Afflicted by Dupuytren’s Disease and Other Inflammatory Conditions

October 14, 2020 11:37:53

180 Life Sciences is a clinical-stage biotechnology company developing anti-tumor necrosis factor (“TNF”) therapies to treat a variety of inflammatory conditions.
Phase 2b/3 clinical trials on fibrosis and inflammation-causing TNF irregularity are currently underway with first results expected in 2021
The company is to be acquired by a SPAC (NASDAQ: KBLM) and will be listed on the Nasdaq Capital Market under ticker symbol ATNF

Pioneering biotech company, 180 Life Sciences Corp. is bringing hope to sufferers of Dupuytren’s Disease and other inflammatory conditions caused by an impaired immune system. Currently, the company has three major programs underway focused on therapies for separate areas of inflammation. These programs are headed by a team of renowned scientists who have already developed blockbuster drugs, discovered an entire drug class and made ground-breaking discoveries in their fields. The programs are exploring therapies expected to bring relief to those afflicted by a variety of TNF conditions, including ‘frozen shoulder,’ Dupuytren disease, postoperative cognitive dysfunction (“POCD”), and non-alcoholic fatty liver disease (“NAFLD”).

TNF is one of those good things, a surfeit of which, can turn out bad. A protein released by white blood cells to mobilize the body’s defenses, i.e. the immune system, TNF plays an essential role in fighting off diseases of many kinds. TNF triggers inflammation to create an environment conducive to healing infected or damaged tissue. Typically, this state of affairs continues just long enough to repair damage to the…

NOTE TO INVESTORS: The latest news and updates relating to 180 Life Sciences are available in the company’s newsroom at http://ibn.fm/180

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Could Dental Mouthwashes Aid in Coronavirus Infection Prevention?

October 14, 2020 10:17:30

By now, you must have heard that hand washing, social distancing, wearing face masks and using a hand sanitizer are valuable tools in the fight against SARS-Cov-2 infection. It now turns out that using a dental mouthwash could also be an additional way to prevent the replication of the coronavirus once it gets into your mouth and throat.

Before you dismiss this suggestion as a wild idea, consider the fact that it was made by none other than the widely respected American Physiological Society. This society was established in 1887 and it brings together all biomedical professionals whose specialty is studying how cells, molecules, tissues and organs function in relation to health and disease. The group publishes 16 peer-reviewed…

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BioMedNewsBreaks – AzurRx BioPharma Inc. (NASDAQ: AZRX) Adds More Sites for Cystic Fibrosis Clinical Trials

October 14, 2020 09:43:08

AzurRx BioPharma (NASDAQ: AZRX) has activated additional clinical trial sites for its trial of MS1819 in cystic fibrosis. The company specializes in the development of nonsystemic, recombinant therapies for gastrointestinal diseases. The company has activated two additional trial sites in Turkey for its Phase 2 combination therapy trial of its lead drug candidate, MS1819. MS1819 is a recombinant lipase for the treatment of exocrine pancreatic insufficiency (“EPI”) in patients suffering from chronic pancreatitis and cystic fibrosis. Patient screening has already been initiated for the new trial sites, with topline data expected by Q2 2021. AzurRx had previously activated six clinical sites in Hungary, where dosing of patients has already begun. This new announcement makes a total of eight identified sites; the company ultimately plans on having twelve European sites active for these clinical trials. “We are truly pleased and encouraged by the interest in our expanding global Phase 2 Combination Trial,” said AzurRx chief medical officer James Pennington, MD, in the press release. “The recently reported interim data suggests promising results and the full data readout is expected in the second quarter of next year. Our investigators in Turkey have been extremely diligent in driving the start-up of this trial in a very efficient and effective manner, and we look forward to our continued work with them.”

To view the full press release, visit https://ibn.fm/oliY8

About AzurRx BioPharma Inc.

AzurRx BioPharma is a biopharmaceutical company specialized in the research and development of nonsystemic biologics for gastrointestinal disorders. The company is focused on the development of its lead drug candidate, MS1819. AzurRx is currently conducting two Phase 2 clinical trials of MS1819: the OPTION 2 monotherapy trial and the combination therapy trial, consisting of MS1819 in conjunction with porcine-derived pancreatic enzyme replacement therapy, the current standard of care. The company is headquartered in New York, NY, with clinical operations in Hayward, California. For more information, visit the company’s website at www.AzurRx.com.

NOTE TO INVESTORS: The latest news and updates relating to AZRX are available in the company’s newsroom at https://ibn.fm/AZRX

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Is Global Health at Risk from Extreme Hot and Extreme Air Pollution Events?

October 13, 2020 13:15:46

Days characterized by extreme air pollution and extreme high heat are increasing in frequency in different parts of the world. For example, New Delhi in India experienced a week of the worst ever air pollution that had ever been recorded anywhere in human history in November last year. Shortly before that extreme event, Western Europe saw two heatwaves that left at least 1,500 people dead. These developments prompted a team at Texas A&M University to investigate what would happen if extreme heat coincided with extreme air pollution.

The researchers used a computer model to analyze the likelihood of extreme heat and extreme air pollution coinciding in South Asia. This particular computer model used data on the trends of greenhouse gas emissions, population…

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Gestational Diabetes Could Accelerate Biological Age in Children

October 13, 2020 13:08:43

According to the work of Rutgers researchers published in the journal Epigenetics, kids who are born to diabetic mothers are prone to aging faster biologically and they may also be more susceptible to high blood pressure and obesity later in life.

The study analyzed more than 1,000 Chinese children born by mothers who had diabetes during pregnancy in order to understand their biological aging process. Of interest to the research team was the in utero exposure of the kids to diabetes and how that affected DNA methylation. Epigenetic methylation looks at how exposure to different conditions and environments accelerates or slows down…

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CNS Pharmaceuticals Inc. (NASDAQ: CNSP) Takes Another Step Closer to Q1 Launch of Brain Cancer Drug Trial

October 13, 2020 13:05:19

CNS Pharmaceuticals is a pre-clinical-stage developer of novel brain cancer-fighting drugs, including its lead candidate Berubicin
The company is working to build on promising results from a 2006 Phase I trial, which provided 44 percent of its limited patient pool with clinically significant improvement in disease stability and one patient with a durable complete response (no evidence of any tumor remaining) for over 14 years
CNS Pharmaceuticals expects to launch a pivotal Phase II trial of Berubicin at the beginning of next year and has been assembling a team of partner companies help with the trial
CNS recently announced that the partner contracted to manufacture the Active Pharmaceutical Ingredient (API) for Berubicin has received a Certificate of Analysis necessary for the drug substance to be used in the clinical trial
The company is also preparing in collaboration with its sub licensed partner, WPD Pharmaceuticals, for the first Phase I pediatric trial of Berubicin
CNS is continuing the pre-clinical development of the company’s second promising cancer-fighting drug candidate, WP1244

Houston, Texas-based biopharmaceutical company CNS Pharmaceuticals (NASDAQ: CNSP) continues to achieve milestones in its drive to defeat glioblastoma multiforme (“GBM”), a relentless type of brain tumor known for very rapid progression and very short survival periods in nearly all patients once they’ve been diagnosed.

“If you get glioblastoma, the sad fact is you’re going to die from that disease,” CNS Pharmaceuticals CEO John Climaco told attendees at the Oppenheimer Fall Healthcare Life Sciences & MedTech Summit in September during a discussion about the aggressive brain tumors and the company’s investment potential as it…

NOTE TO INVESTORS: The latest news and updates relating to CNSP are available in the company’s newsroom at https://ibn.fm/CNSP

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Predictive Oncology Inc. (NASDAQ: POAI) CEO Schwartz Pens Letter to Shareholders, Elaborates on Ongoing Company Developments

October 13, 2020 12:24:51

Predictive Oncology’s CEO Carl Schwartz published open letter to company’s shareholders
Schwartz elaborated on various developments within each of POAI’s divisions, has reiterated his optimism on company’s operations going forward
CEO also revealed that company’s revenue trends have stabilized and are now on upward trend with cash burn beginning to decline
Company also revealed its ability to access over $10 million in undrawn equity lines of credit

Carl Schwartz, the CEO of Predictive Oncology (NASDAQ: POAI), a knowledge-driven medicine company that focuses on applying data and artificial intelligence (“AI”) to cancer personalized medicine and drug discovery, has recently published a letter to the company’s shareholders elaborating on the company’s latest achievements as well as their prospects going forward (https://ibn.fm/L1mA8).

Within his letter, Schwartz addressed the latest developments within each of the company’s business verticals and stressed that in spite of the tumultuous global economy, Predictive Oncology was witnessing both stable and rising revenues along with declining levels of cash burns. Schwartz also detailed that the company’s balance sheet was still quite resilient with access to over $10 million in equity capital able to be drawn down from their…

NOTE TO INVESTORS: The latest news and updates relating to POAI are available in the company’s newsroom at http://ibn.fm/POAI

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BioMedNewsBreaks – Lineage Cell Therapeutics Inc. (NYSE American: LCTX) (TASE: LCTX), Leading Cancer Charity Announce Encouraging Preliminary Phase 1 Study Results

October 13, 2020 11:40:42

Lineage Cell Therapeutics (NYSE American: LCTX) (TASE: LCTX) and Cancer Research UK have released encouraging results from an ongoing Phase 1 clinical study of VAC2 in non-small cell lung cancer (“NSCLC”). LCTX, a clinical-stage biotechnology company developing novel cell therapies for unmet medical needs, and Cancer Research UK, the world’s leading cancer charity dedicated to saving lives through research, worked together on the study, which focused on VAC2. Highlights of the study include potent induction of immune responses observed with the VAC2 vaccine and peripheral antigen-specific immunogenicity above 3% observed at multiple timepoints. In addition, VAC2 appeared to be well tolerated with no unexpected adverse events. The drug has demonstrated remarkably potent induction of immune responses in all patients dosed to date, with high levels of peripheral antigen-specific immunogenicity observed at multiple time points and confirmed by multimer staining. Based on these results, Lineage intends to seek to further study VAC2 in combination with therapies considered biologically complementary to VAC2, such as chemotherapy and the immune cell protectant properties offered by anti-PD1 immunotherapy. “Interestingly, one patient experienced a radiological response following chemotherapy subsequent to VAC2 treatment,” said Lineage CEO Brian Culley in the press release. “Although anecdotal and occurring after the patient had completed the VAC2 trial, responses in this setting are rare and support further investigation. Dendritic cells are the most potent antigen-presenting cells in the body and harnessing their power to accurately deliver information about foreign material is re-emerging as an attractive therapeutic modality based on their consistent safety profile and increasing knowledge of how to deploy them in the clinical setting. As a leader in the field of cell therapy, Lineage aims to advance the current VAC2 product candidate and identify ways to expand the VAC platform through internally owned and externally partnered antigens.”

To view the full press release, visit https://ibn.fm/H3KFc

About Lineage Cell Therapeutics Inc.

Lineage Cell Therapeutics is a clinical-stage biotechnology company developing novel cell therapies for unmet medical needs. Lineage’s programs are based on its robust proprietary cell-based therapy platform and associated in-house development and manufacturing capabilities. With this platform, Lineage develops and manufactures specialized, terminally differentiated human cells from its pluripotent and progenitor cell-starting materials. These differentiated cells are developed to either replace or support cells that are dysfunctional or absent due to degenerative disease or traumatic injury or administered as a means of helping the body mount an effective immune response to cancer. Lineage’s clinical programs are in markets with billion dollar opportunities and include three allogeneic (“off-the-shelf”) product candidates: (i) OpRegen(r), a retinal pigment epithelium transplant therapy in Phase 1/2a development for the treatment of dry age-related macular degeneration, a leading cause of blindness in the developed world; (ii) OPC1, an oligodendrocyte progenitor cell therapy in Phase 1/2a development for the treatment of acute spinal cord injuries; and (iii) VAC, an allogeneic dendritic cell therapy platform for immuno-oncology and infectious disease, currently in clinical development for the treatment of non-small cell lung cancer and in preclinical development for additional cancers and as a vaccine against infectious diseases, including SARS-CoV-2, the virus that causes COVID-19. For more information, visit www.lineagecell.com

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BioMedNewsBreaks – 180 Life Sciences Corp. Announces New Board Appointments

October 13, 2020 11:20:20

KBL Merger Corp. IV (NASDAQ: KBLM), a special purpose acquisition company (“SPAC”) that previously entered a definitive agreement to acquire 180 Life Sciences, a clinical-stage biotechnology company, recently announced the appointment of Professor Richard Barker, Larry Gold Md., Shoshana Shendelman PhD., and Donald McGovern Jr. to its board of directors, upon completion of the business combination. 180 Life Sciences is led by Dr. James Woody, who previously served as the founding CEO of OncoMed Pharmaceuticals and president and general manager of Roche Bioscience. “I’m pleased to welcome Richard, Larry, Shoshana and Donald to our board of directors,” Dr. Woody said in the press release. “I have known Larry for many years, and I admire his brilliant work in building Somalogic into the premier worldwide protein identification company. Don and I worked on a biotech board together and his vast PWC international experience will be of immense value to 180 Life Sciences. Richard joins, recommended by Sir Marc Feldman, with his broad and skillful experience in science, management and drug development, having served on the Celgene Board. Shoshana joins as the CEO of Applied Therapeutics, an enterprising biotechnology company she founded and has developed into a dynamic organization. Her recent successful experience in the financing arenas will be exceptionally valuable to our team.”

To view the full press release, visit https://ibn.fm/6xGSJ

About 180 Life Sciences Corp.

180 Life Sciences is a clinical-stage biotechnology company focused on the development of novel drugs that fulfill unmet needs in inflammatory diseases, fibrosis and pain by leveraging the combined expertise of luminaries in therapeutics from Oxford University, the Hebrew University and Stanford University. 180 Life Sciences is leading the research into solving one of the world’s biggest drivers of disease – inflammation. The company is driving groundbreaking study into clinical programs, which are seeking to develop novel drugs addressing separate areas of inflammation for which there are no effective therapies. The company’s primary platform is a novel program to treat fibrosis and inflammation using anti-TNF, with its lead program in phase 2b/3 clinical trials. For more information about the company, visit www.180LifeSciences.com.

NOTE TO INVESTORS: The latest news and updates relating to 180 Life Sciences are available in the company’s newsroom at http://ibn.fm/180

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BioMedNewsBreaks – Processa Pharmaceuticals Inc. (NASDAQ: PCSA) Appoints Serial Entrepreneur as New Chief Operating Officer

October 13, 2020 11:16:18

Processa Pharmaceuticals (NASDAQ: PCSA), a clinical-stage biopharmaceutical company developing products to improve survival and/or quality of life for patients who have high unmet medical needs, has appointed a new chief operating officer. Michael Floyd, a serial entrepreneur who has formed several life science organizations and served as a senior executive in those organizations, will be taking over that role. Floyd is well suited for the new position as many of the companies he has been involved in were focused on the development of products to treat infectious and rare diseases as well as the development of oncology drugs. Most recently, he co-founded Elion Oncology which licensed PCS6422 to Processa. In addition, he founded Neurologic, an early-stage enterprise that in-licensed technology from the NIH for a diagnostic test for Alzheimer’s disease. He was also CEO at the North American subsidiary of Arpida Ltd., overseeing the organization of the phase 3 program for the NDA submission of an MRSA drug. And at Gentium, SpA, he led U.S. efforts to remediate the NDA for defibrotide. “Adding Mike to our leadership team will enable me to spend more time focusing on our long-term strategic direction and our pipeline,” Processa CEO and chairman David Young, MD, stated in the press release. “Mike is a proven life science entrepreneur with a demonstrated track record of successfully delivering results. He has the leadership capabilities we are looking for to help us grow Processa.”

To view the full press release, visit https://ibn.fm/UwLvl

About Processa Pharmaceuticals Inc.

The mission of Processa has been to develop products where existing clinical evidence of efficacy already exists in unmet medical need conditions, medical conditions where patients need treatment options that will improve survival and/or quality of life. The company has assembled a proven regulatory science development team, management team and Board of Directors. The Processa development team has been involved with more than 30 drug approvals by the FDA (including drug products targeted to orphan disease conditions) and 100 FDA meetings. For more information, visit www.ProcessaPharmaceuticals.com.

NOTE TO INVESTORS: The latest news and updates relating to PCSA are available in the company’s newsroom at https://ibn.fm/PCSA

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BioMedNewsBreaks – DarioHealth Corp. (NASDAQ: DRIO) Platform Selected for Integration in Vitality’s Gateway Flex

October 13, 2020 10:22:18

DarioHealth (NASDAQ: DRIO), a pioneer in the global digital-therapeutics market, today announced that Vitality Group has chosen the company’s digital therapeutics solutions for inclusion in Vitality’s new Gateway Flex offering. According to the update, Gateway Flex enables employers to personalize the health-care experience to meet the diverse and rapidly changing needs of their employees and allows employers to pay only for solutions in which their employees engage. “We believe that our inclusion in Vitality’s Gateway Flex offering represents another recent validation of our digital therapeutic solution and reinforces our position as a partner of choice,” Rick Anderson, president and general manager of North America at DarioHealth, said in the press release. “Gateway Flex offers employers simplicity, flexibility and cost-effectiveness, and complements our unique open platform that allows us to scale and integrate into an increasingly complex and value- driven ecosystem of employer benefit providers. We look forward to working together to make our innovative solution broadly available to Vitality’s vast customer base.”

To view the full press release, visit https://ibn.fm/PySeF

About DarioHealth Corp.

NOTE TO INVESTORS: The latest news and updates relating to DRIO are available in the company’s newsroom at http://ibn.fm/DRIO

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Social Media Could Trigger Secondary Trauma, Depression During Pandemic

October 12, 2020 12:36:48

Social media was a game-changer when it first came onto the scene. Sites like Facebook and Twitter allowed people to share and connect like they never had, and for a while, no one noticed just how harmful social media could potentially be. But a few years into the social media craze we now know that while it has its benefits, social media can have quite a negative effect on mental health, resulting in anything from depression and anxiety to cyber-bullying and feelings of inadequacy.

According to researchers at Penn State and Jinan University, social media has also caused adverse effects in some individuals during the pandemic. The researchers say that excessive use of social media for updates on the coronavirus pandemic could trigger secondary…

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BioMedNewsBreaks – Vivos Therapeutics Inc. Files Registration Statement for Proposed $20M Initial Public Offering

October 12, 2020 12:01:51

Vivos Therapeutics, a medical technology company that offers novel and proprietary alternatives for treating mild-to-moderate obstructive sleep apnea, on Friday announced that is has filed a registration statement on Form S-1 with the U.S. Securities and Exchange Commission (“SEC”) relating to the proposed initial public offering of its common stock. According to the update, application has been made for listing the common stock on the Nasdaq Capital Market under the ticker symbol “VVOS.” The proposed $20,000,000 offering (not including the underwriters’ over-allotment option), which is subject to market conditions with no assurance as to its actual completion or terms, has a proposed price range of between $5.00 and $7.00 per share. Roth Capital Partners is acting as lead book-running manager and representative of the underwriters for the proposed offering. Craig-Hallum Capital Group and National Securities Corporation, a wholly owned subsidiary of National Holdings Corporation (NASDAQ: NHLD), are acting as co-managers of the proposed offering.

To view the full press release, visit https://ibn.fm/3wFu3

About Vivos Therapeutics Inc.

Vivos Therapeutics is an emerging global leader in the treatment of obstructive sleep apnea (“OSA”), a debilitating condition affecting nearly 1 billion people worldwide. Headquartered in Denver, Colorado, the company utilizes proprietary, groundbreaking technology; a proven, go-to-market strategy; and a powerful executive team dedicated to changing the face of health care by helping people of all ages properly breathe and sleep. At the core of Vivos’ mission to eradicate OSA is the Vivos System(R), a revolutionary clinical breakthrough in the treatment of sleep apnea caused by craniofacial anatomy development. The Vivos System multidisciplinary treatment protocol involves collaboration between physicians, specially trained dentists who have completed advanced training in craniofacial sleep medicine, and other ancillary health-care providers. In support of its growth strategy, Vivos has established FDA-approved and registered manufacturing facilities in the United States, Canada and Asia. For more information, visit the company’s website at www.VivosLife.com.

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Mental Health Misconceptions You Shouldn’t Fall For

October 12, 2020 11:18:52

Today, it’s widely accepted that mental health has a great bearing on quality of life and that individuals with mental health conditions are as deserving of compassion as anyone else. But even with all the information we have at our disposal, plenty of myths about mental health persist. These myths increase the stigma around mental health and prevent people who need medical help from getting the help they need. So as World Mental Health Day approaches, here are 6 mental health myths you shouldn’t fall for;

Mental health problems are uncommon. You would be surprised to learn just how prevalent mental health problems are. Back in 2001, the World Health Organization (“WHO”) estimated that “1 in 4 people in the world will be affected by mental or neurological disorders at some point in their lives,” and that was before the Great Recession of 2008 and the coronavirus pandemic. At the moment, 460 million people in the world are living with mental health conditions, with WHO classifying mental…

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BioMedNewsBreaks – CNS Pharmaceuticals Inc. (NASDAQ: CNSP) Highlights New Glioblastoma-Focused Segment Airing on Lifetime TV

October 12, 2020 08:52:33

CNS Pharmaceuticals (NASDAQ: CNSP), a biopharmaceutical company specializing in the development of novel treatments for primary and metastatic cancers of the brain and central nervous system, today highlighted a new segment from The Balancing Act titled, “Behind the Mystery,” which will air on Lifetime TV and focus on glioblastoma. The segment, live this morning, follows the unique story of a glioblastoma patient and clinical insights regarding the rare and difficult-to-treat disease from Dr. Sigmund Hsu, a member of CNS Pharmaceuticals’ Scientific Advisory Board. In addition, a re-airing of the segment is planned for October 23, 2020. “It is encouraging to see The Balancing Act bring awareness to such a devastating disease. Glioblastoma is one of the most aggressive primary brain cancers in adults, with approximately 13,000 new patients diagnosed each year in the U.S.—the highest diagnosis rate of all malignant brain tumors,” CNS Pharmaceuticals CEO John Climaco said in the news release. “At CNS, we are committed to our development efforts in glioblastoma.”

To view the segment and hear the story, visit https://ibn.fm/Jfqk6

To view the full article, visit https://ibn.fm/l7K8c

About CNS Pharmaceuticals Inc.

CNS Pharmaceuticals is developing novel treatments for primary and metastatic cancers of the brain and central nervous system. Its lead drug candidate, Berubicin, is proposed for the treatment of glioblastoma multiforme (“GBM”), an aggressive and incurable form of brain cancer. CNS holds a worldwide exclusive license to the Berubicin chemical compound and has acquired all data and know-how from Reata Pharmaceuticals Inc. related to a completed Phase 1 clinical trial with Berubicin in malignant brain tumors, which Reata conducted in 2006. In this trial, 44% of patients experienced a statistically significant improvement in clinical benefit. This 44% disease control rate was based on 11 patients (out of 25 evaluable patients) with stable disease, plus responders. One patient experienced a durable complete response and remains cancer-free as of February 20, 2020. These Phase 1 results represent a limited patient sample size and, while promising, are not a guarantee that similar results will be achieved in subsequent trials. By the end of 2020, CNS expects to commence a Phase 2 clinical trial of Berubicin for the treatment of GBM in the U.S., while a sub-licensee partner undertakes a Phase 2 trial in adults and a first-ever Phase 1 trial in pediatric GBM patients in Poland. Its second drug candidate, WP1244, is a novel DNA binding agent that has shown in preclinical studies that it is 500 times more potent than the chemotherapeutic agent daunorubicin in inhibiting tumor cell proliferation. For more information, visit the company’s website at www.CNSPharma.com.

NOTE TO INVESTORS: The latest news and updates relating to CNSP are available in the company’s newsroom at https://ibn.fm/CNSP

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Research Identifies Two Types of Parkinson’s Disease

October 9, 2020 13:42:16

For long, doctors and researchers have been baffled by the myriad of different symptoms that people with Parkinson’s disease exhibit. According to new research that has just been published in a neurological journal called Brain, it now turns out that Parkinson’s is not just a single disease. Rather, the condition has two variants which should be managed differently.

This eye-opening research was done by a team from Aarhus University Hospital and Aarhus University in Denmark. Professor Per Borghammer and Jacob Horsager, M.D. are the researchers…

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BioMedNewsBreaks – Processa Pharmaceuticals Inc. (NASDAQ: PCSA) Featured in Simply Wall St Article

October 9, 2020 11:18:38

Processa Pharmaceuticals (NASDAQ: PCSA), a clinical-stage biopharmaceutical company focused on the development of drug products for patients with high unmet medical need conditions or no alternative treatment options, was featured in a Simply Wall St article. The piece highlights PCSA Co-Founder Patrick Lin’s recent stock purchase at near current price. The article reads, “Potential Processa Pharmaceuticals Inc. (NASDAQ: PCSA) shareholders may wish to note that the Co-Founder, Patrick Lin, recently bought US$125k worth of stock, paying US$4.00 for each share. While that’s a very decent purchase to our minds, it was proportionally a bit modest, boosting their holding by just 8.5%. In fact, the recent purchase by Patrick Lin was the biggest purchase of Processa Pharmaceuticals shares made by an insider individual in the last twelve months, according to our records. That means that an insider was happy to buy shares at around the current price of US$4.08. . . . While we always like to see insider buying, it’s less meaningful if the purchases were made at much lower prices, as the opportunity they saw may have passed. Happily, the Processa Pharmaceuticals insiders decided to buy shares at close to current prices.”

To view Simply Wall St’s latest analysis for Processa Pharmaceuticals, visit https://ibn.fm/FRRP9

To view the full article, visit https://ibn.fm/IXeAR

About Processa Pharmaceuticals Inc.

The mission of Processa has been to develop products where existing clinical evidence of efficacy already exists in unmet medical need conditions — medical conditions where patients need treatment options that will improve survival and/or quality of life. The company has assembled a proven regulatory science development team, management team and board of directors. The Processa development team has been involved with more than 30 drug approvals by the FDA (including drug products targeted to orphan disease conditions) and 100 FDA meetings. For more information, visit the company’s website at www.ProcessaPharma.com.

NOTE TO INVESTORS: The latest news and updates relating to PCSA are available in the company’s newsroom at https://ibn.fm/PCSA

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BioMedNewsBreaks – Cardiff Oncology Inc. (NASDAQ: CRDF) Announces Pricing of Underwritten Public Offering

October 9, 2020 10:43:48

Cardiff Oncology (NASDAQ: CRDF), a clinical-stage oncology therapeutics company developing drugs to treat cancers with the greatest medical need for new treatment options, recently announced the pricing of its previously announced underwritten public offering of 6,500,000 shares of its common stock at a public offering price of $13.50 per share. Cardiff Oncology anticipates receipt of approximately $88 million in gross proceeds from the offering, which is expected to close on or about October 2, 2020, subject to the satisfaction of customary conditions. The company has granted the underwriters a 30-day option to purchase up to an additional 975,000 shares at the public offering price, less underwriting discounts and commissions. Cardiff Oncology intends to use the net proceeds for clinical development of its product candidate, onvansertib, as well as for working capital and other general corporate purposes.

To view the full article, visit https://ibn.fm/U7MWZ

About Cardiff Oncology Inc.

Cardiff Oncology (formerly Trovagene Inc.) is a clinical-stage biotechnology company with the singular mission of developing new treatment options for cancer patients in indications with the greatest medical need. The company’s goal is to overcome resistance, improve response to treatment and increase overall survival. Cardiff Oncology is developing onvansertib, a first-in-class, third-generation Polo-like Kinase 1 (“PLK1”) inhibitor, in combination with standard-of-care chemotherapy and targeted therapeutics. Its clinical development programs incorporate tumor genomics and biomarker technology to enable assessment of patient response to treatment. Cardiff Oncology has three ongoing clinical programs that are demonstrating the safety and efficacy of onvansertib: a Phase 1b /2 study of onvansertib in combination with FOLFIRI/Avastin(R) in KRAS-mutated metastatic colorectal cancer (“mCRC”); a Phase 2 study of onvansertib in combination with Zytiga(R) (abiraterone)/prednisone in metastatic castration-resistant prostate cancer (“mCRPC”); and a Phase 2 study of onvansertib in combination with decitabine in relapsed or refractory acute myeloid leukemia (“AML”). For more information, please visit www.CardiffOncology.com.

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Early Morning Coffee Could Impair Metabolism, New Research Suggests

October 9, 2020 10:24:49

October 1st was International Coffee Day, and it is estimated that half of all U.S. adults consume coffee on a daily basis. You might therefore be no stranger to taking a strong cup of coffee each time you wake up feeling groggy. But, did you know that the early morning cup of strong coffee you take could be compromising your metabolism and making it harder for your blood glucose level to be regulated? New research done at the University of Bath (UK) strongly suggests that this is the case.

The research team headed by Harry Smith performed overnight experiments on 29 men and women. In one of the experiments, the study participants were asked to sleep…

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BioMedNewsBreaks – CNS Pharmaceuticals Inc. (NASDAQ: CNSP) Begins Manufacturing of Lead Drug Candidate in Europe

October 9, 2020 10:12:22

CNS Pharmaceuticals (NASDAQ: CNSP), a biopharmaceutical company specializing in the development of novel treatments for primary and metastatic cancers of the brain and central nervous system, today announced that its European manufacturer, BSP Pharmaceuticals S.p.A. (“BSP”), has begun the manufacturing process for Berubicin Drug Product, its lead drug candidate for the treatment of glioblastoma multiforme (“GBM”). GBM is an aggressive form of brain cancer currently considered incurable. “Our preparations for filing an IND for Berubicin require continued execution in both our clinical and manufacturing initiatives,” CNS Pharmaceuticals CEO John Climaco said in the news release. “With the manufacturing of our Berubicin Drug Product in Europe, we continue to advance closer toward an IND filing for Berubicin, which we expect to submit later this quarter. We have also made significant progress on the clinical front and recently engaged Worldwide Clinical Trials as the contract research organization, Image Analysis Group (‘IAG’) as the imaging partner, and Berry Consultants as a biostatistical advisor for our Phase 2 trial design. We have also added Dr. Patrick Wen, a renowned neuro-oncologist, to our Scientific Advisory Board. Our laser focus remains on initiating a U.S. Phase 2 trial for Berubicin in Q1 of 2021 and we continue to demonstrate our ability to execute our operational and clinical plans toward that goal.”

To view the full article, visit https://ibn.fm/bvtlq

About CNS Pharmaceuticals Inc.

CNS Pharmaceuticals is developing novel treatments for primary and metastatic cancers of the brain and central nervous system. Its lead drug candidate, Berubicin, is proposed for the treatment of glioblastoma multiforme (“GBM”), an aggressive and incurable form of brain cancer. CNS holds a worldwide exclusive license to the Berubicin chemical compound and has acquired all data and know-how from Reata Pharmaceuticals Inc. related to a completed Phase 1 clinical trial with Berubicin in malignant brain tumors, which Reata conducted in 2006. In this trial, 44% of patients experienced a statistically significant improvement in clinical benefit. This 44% disease control rate was based on 11 patients (out of 25 evaluable patients) with stable disease, plus responders. One patient experienced a durable complete response and remains cancer-free as of February 20, 2020. These Phase 1 results represent a limited patient sample size and, while promising, are not a guarantee that similar results will be achieved in subsequent trials. By the end of 2020, CNS expects to commence a Phase 2 clinical trial of Berubicin for the treatment of GBM in the U.S., while a sub-licensee partner undertakes a Phase 2 trial in adults and a first-ever Phase 1 trial in pediatric GBM patients in Poland. Its second drug candidate, WP1244, is a novel DNA binding agent that has shown in preclinical studies that it is 500 times more potent than the chemotherapeutic agent daunorubicin in inhibiting tumor cell proliferation. For more information, visit the company’s website at www.CNSPharma.com.

NOTE TO INVESTORS: The latest news and updates relating to CNSP are available in the company’s newsroom at https://ibn.fm/CNSP

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Analysis Uncovers a Link Between Obesity & Food Insecurity

October 9, 2020 08:12:42

Over the years, obesity has become a pressing issue in the U.S., with nearly 30% of Americans afflicted by the condition. Although the assumption is that extreme weight gain is usually caused by binge eating, a variety of factors are usually at play. One such factor is food insecurity, which is defined as the lack of access to enough food for an active, healthy life. Internationally, food insecurity is usually caused by the frequency of conflict as well as the climate-related failure of harvests but in the U.S., it is most often due to limited financial resources.

According to a recent analysis of trends in food security, the association between food insecurity and obesity has doubled since 1999-2000. The analysis was based on data collected through the National Health and Nutrition Examination Survey (“NHANES”) from over 46,000 adults in the U.S. The Pennington Biomedical Research Center in Baton Rouge, LA analyzed data collected from 1999 to 2016, with researchers…

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BioMedNewsBreaks – VistaGen Therapeutics (NASDAQ: VTGN) Featured in Research Report

October 8, 2020

October 8, 2020 14:24:36

VistaGen Therapeutics (NASDAQ: VTGN), a clinical-stage biopharmaceutical company developing new generation medicines for anxiety, depression and other central nervous system (“CNS”) disorders, was featured in a recent research report by Aegis Capital Corp. The report reads, “VistaGen is developing multiple therapeutic candidates for the treatment of anxiety, depression, and other CNS indications. VistaGen’s development pipeline includes PH94B, a neuroactive nasal spray targeting Social Anxiety Disorder (‘SAD’), among other conditions, PH10, an additional neuroactive nasal spray for indications including Major Depressive Disorder (‘MDD’), and AV-101 an oral drug for psychiatric and other CNS disorders. We believe Phase 2 data in PH94B and PH10 strongly supports proof of concept, including compelling safety and efficacy data that likely differentiate these assets from existing treatments in crucial ways that could be supportive of market adoption if and when approved.”

To view the full report, visit https://ibn.fm/eLamD

About VistaGen Therapeutics

NOTE TO INVESTORS: The latest news and updates relating to VTGN are available in the company’s newsroom at https://ibn.fm/VTGN

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BioMedNewsBreaks – CB Scientific Inc. (CBSC) Announces Thailand Launch of My-Cardia ECG Product Line, Services

October 8, 2020

October 8, 2020 11:25:59

CB Scientific (OTC: CBSC), engaged in providing innovative products and services for the ambulatory noninvasive cardiac monitoring space, today announced the targeted start of cardiac lab services operations in the country of Thailand through CBSC’s exclusive authorized distributor, Mango Wellness Co. Ltd. (“MWC”) and My Cardia Thailand Co. Ltd. (“MCT”), beginning Oct. 29, 2020. Under the agreement, MWC and MCT will be the exclusive distributor for CBSC’s proprietary FDA and CE-cleared EKG my-Cam Cardiac Event Monitor, the interactive cloud-based My-Cardia acquisition software, and the associated smartphone apps for both iOS and Android platforms in Thailand. The My-Cardia product line is designed specifically for the Remote Cardiac Ambulatory ECG market to help in the detection of abnormal heart rhythms while providing improved compliance for the patient and more timely, convenient and accurate information for the physician. “This launch, together with the upcoming targeted distribution start-ups in Malaysia and Singapore in the coming months and our continued work towards NMPA (National Medical Products Administration, formerly CFDA) certification in China, will go a long way towards helping our company establish a solid footprint in the Ambulatory noninvasive ECG monitoring market in Asia,” CBSC CEO Charles Martin said in the news release.

To view the full press release, visit https://ibn.fm/C9ybr

About CB Scientific Inc.

CB Scientific is a publicly traded company that, through its U.S. and international subsidiaries, provides innovative products and services in the ambulatory non-invasive cardiac monitoring space. For more information about the company, visit www.CBScientificInc.com.

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BioMedNewsBreaks – Why VistaGen Therapeutics (NASDAQ: VTGN) Is ‘One to Watch’

October 7, 2020 13:49:16

VistaGen Therapeutics (NASDAQ: VTGN) is a biopharmaceutical company committed to developing and commercializing a new generation of medications that go beyond the standard of care for anxiety, depression and other central nervous system (“CNS”) disorders. Based out of South San Francisco, California, the “Birthplace of Biotechnology,” VistaGen is headquartered among the largest cluster of biotechnology companies in the world. A recent article discussing the company reads, “VistaGen currently has three innovative CNS drug candidates in its pipeline: PH94B, PH10 and AV-101. With a differentiated mechanism of action and an exceptional safety profile in all clinical studies to date, each of VistaGen’s three drug candidates offers significant commercialization potential in multiple large CNS markets.”

To view the full article, visit https://ibn.fm/N9ZB3

About VistaGen Therapeutics

VistaGen is a clinical-stage biopharmaceutical company developing new generation medicines for anxiety, depression and other CNS disorders where the current standard of care is inadequate, resulting in high unmet need. Each of VistaGen’s three drug candidates has a differentiated mechanism of action, an exceptional safety profile in all studies to date and therapeutic potential in multiple CNS markets. For more information, please visit www.VistaGen.com.

NOTE TO INVESTORS: The latest news and updates relating to VTGN are available in the company’s newsroom at https://ibn.fm/VTGN

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Heading Soccer Balls Causes More Damage to Females than Males

October 7, 2020 12:47:38

Today, it is common to see members of a female soccer team training close to the ground that is being used by their male counterparts, and this is pleasing given how far society has come before accepting that females can participate in contact sports. However, lots of sports scientists noticed that females were complaining more about the effects of heading the ball when compared to their male counterparts. It now turns out that there is a scientific reason for that as explored below.

According to a study that was led by Dr. Michael Lipton, a neuroscientist based at the Albert Einstein College of Medicine, women suffer five times the amount of brain damage as males who head the ball during soccer games. The study also found that women take longer to recover from the resultant…

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BioMedNewsBreaks – Marizyme Inc. (MRZM) Closes Acquisition of Somulation Inc., $7M Private Placement

October 7, 2020 11:07:31

Marizyme (OTC: MRZM), a client of Univest Securities LLC, a full-service investment bank and securities broker-dealer firm and a member of FINRA and SIPC, recently closed the acquisition of Somulation Inc. and a private placement for $7,000,240 to which Univest Securities acted as the exclusive investment bank and sole-placement agent. According to the update, the Marizyme acquisition of Somahlution Inc. included all of Somahlution LLC’s assets including its DuraGraft(R) intellectual property, Somaceutica intellectual property and derivative works. In addition, Univest Securities raised a total of $7,000,240 in gross proceeds in a private placement offering with common shares only for Marizyme, with a total of 5,600,192 shares each sold at an offering price of $1.25. Marizyme plans to use the proceeds to expand sales of DuraGraft in Europe and to begin to seek U.S. FDA approval. “We are excited to complete this transaction and most importantly bring on the seasoned technical leadership of the Somahlution’s team,” Marizyme’s Executive Chairman James Sapirstein said in the press release. “In addition, we are grateful to Univest Securities and our new investors for the trust they are placing in us to deliver strong shareholder value for Marizyme. Somahlution’s platform technology has enabled the development of a robust product pipeline with the potential to address unmet medical needs and reduce disease burden not only in vascular grafting indications but also indications involving tissue and fat grafting and organ transplant. DuraGraft protects graft tissue from harvesting through anastomosis and is used as a treatment to maintain the structural and functional integrity of free vascular grafts. The use of DuraGraft is associated with reductions of post-CABG complications associated with graft disease and failure: Myocardial Infarction, Repeat Revascularization and other Major Adverse Cardiac Events.”

To view the full press release, visit https://ibn.fm/MZOw0

About Marizyme Inc.

Marizyme is a development-stage company dedicated to the commercialization of innovative therapies that address the urgent unmet needs relating to higher mortality and costs in the acute care space. Specifically, Marizyme will focus its efforts on expanding the applications for its technologies to dental care, wound healing, thrombosis and other tissue preserving uses. For more information, visit www.Marizyme.com or www.Somahlution.com.

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BioMedNewsBreaks – Genprex Inc. (NASDAQ: GNPX) CEO Scheduled to Present at LD Micro Event

October 7, 2020 09:53:31

Genprex (NASDAQ: GNPX), a clinical-stage gene therapy company developing potentially life-changing technologies for patients with cancer and diabetes, is slated to present at an upcoming LD Micro virtual event. GNPX’s Zoom presentation is scheduled for Wednesday, Oct. 14, at 11 a.m. ET. The presentation will feature Genprex president and CEO Rodney Varner, who will deliver a corporate presentation and then participate in a Q&A. Investors and others interested in viewing the presentation can register at https://ibn.fm/MiDEy.

To view the full press release, visit https://ibn.fm/RdBSZ

About Genprex Inc.

Genprex is a clinical-stage gene therapy company developing potentially life-changing technologies for patients with cancer and diabetes. Genprex’s technologies are designed to administer disease-fighting genes to provide new treatment options for large patient populations with cancer and diabetes who currently have limited treatment options. Genprex works with world-class institutions and collaborators to in-license and develop drug candidates to further its pipeline of gene therapies in order to provide novel treatment approaches. The company’s lead product candidate, GPX-001 (quaratusugene ozeplasmid), is being evaluated as a treatment for non-small cell lung cancer (“NSCLC”). GPX-001 has a multimodal mechanism of action that has been shown to interrupt cell signaling pathways that cause replication and proliferation of cancer cells; re-establish pathways for apoptosis, or programmed cell death, in cancer cells; and modulate the immune response against cancer cells. GPX-001 has also been shown to block mechanisms that create drug resistance. In January 2020, the U.S. Food and Drug Administration granted Fast Track Designation for GPX-001 for NSCLC in combination therapy with osimertinib (AstraZeneca’s Tagrisso(R)) for patients with “EFGR” mutations whose tumors progressed after treatment with osimertinib alone. For more information, please visit the company’s website at www.Genprex.com.

NOTE TO INVESTORS: The latest news and updates relating to GNPX are available in the company’s newsroom at http://ibn.fm/GNPX

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BioMedNewsBreaks – Processa Pharmaceuticals Inc. (NASDAQ: PCSA) Announces Closing of Public Offering

October 7, 2020 09:27:41

Processa Pharmaceuticals (NASDAQ: PCSA) has closed its previously announced underwritten public offering of 4,800,000 shares of common stock, which were offered to the public for $4 per share. The clinical-stage biopharmaceutical company, which focuses on the development of drug products intended to provide treatment for and improve the survival and/or quality of life of patients who have a high unmet medical need condition or who have no alternative treatment, announced that the public offering resulted in gross proceeds of approximately $19.2 million. PCSA has filed a registration statement relating to the securities being sold with the Securities and Exchange Commission (“SEC”); the filing was effective on Oct. 1, 2020. A final prospectus has also been filed with the SEC. Copies of the final prospectus may be obtained from the Craig-Hallum Capital Group, which acted as joint book-running managers for the offering, along with The Benchmark Company. National Securities Corporation acted as co-manager for the offering.

To view the full press release, visit https://ibn.fm/0thEx

About Processa Pharmaceuticals Inc.

NOTE TO INVESTORS: The latest news and updates relating to PCSA are available in the company’s newsroom at https://ibn.fm/PCSA

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BioMedNewsBreaks – 180 Life Sciences Corp. Continues to Broaden Global IP Portfolio, Expand Internal Pipeline

October 7, 2020 08:55:15

KBL Merger Corp. IV (NASDAQ: KBLM), a special purpose acquisition company (“SPAC”) that previously entered a definitive agreement to acquire 180 Life Sciences, a clinical-stage biotechnology company, on Tuesday announced continued expansion of 180 Life Sciences’ robust intellectual property (“IP”) portfolio. According to the update, 180 Life Sciences is an applicant and licensee of a broad and growing patent portfolio for three major drug platforms in the areas of inflammation, fibrosis and pain. The portfolio covers 14 patent families with 42 patents issued and 32 pending in several important jurisdictions, including the United States, Canada, Europe, Australia, Japan and China. Of the many recent filings and grants in the company’s extensive portfolio, the EU Patent and Trademark Office in June 2020 granted patent number 2547363 “Methods of Prevention or Treatment of Triggered Inflammatory Reactions Using TNF Alpha Antagonist.” “The issuance of our European patents significantly strengthens the IP portfolio governing our lead program,” Dr. James Woody, CEO of 180 Life Sciences, said in the news release. “We are committed to broadening our global patent estate as we continue to expand our internal pipeline and increase patient access to innovative therapies. Having this most recent patent awarded in the EU is important as it provides validation in the 12 largest countries in the EU, including the UK, and provides the platform to be able to expand clinical trials, commercialization and partnering efforts throughout Europe. We look forward to achieving additional milestones by the end of 2020.”

To view the full press release, visit https://ibn.fm/chN6V

About 180 Life Sciences Corp.

180 Life Sciences is a clinical-stage biotechnology company focused on the development of novel drugs that fulfill unmet needs in inflammatory diseases, fibrosis and pain by leveraging the combined expertise of luminaries in therapeutics from Oxford University, the Hebrew University and Stanford University. 180 Life Sciences is leading the research into solving one of the world’s biggest drivers of disease – inflammation. The company is driving groundbreaking study into clinical programs, which are seeking to develop novel drugs addressing separate areas of inflammation for which there are no effective therapies. The company’s primary platform is a novel program to treat fibrosis using anti-TNF, with its lead program in phase 2b/3 clinical trials. For more information, visit the company’s website at www.180LifeSciences.com.

NOTE TO INVESTORS: The latest news and updates relating to 180 Life Sciences are available in the company’s newsroom at http://ibn.fm/180

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Pioneer Research Unveils Electronic Skin That Can Feel Pain

October 7, 2020 08:43:18

Researchers from RMIT University in Australia have created an artificial skin that electronically reacts to pain stimuli like human skin. This has paved the way for intelligent robotics and far better prosthetics to be developed as well as the development of alternative skin grafts which are non-invasive.

The prototype device imitates the body’s instant feedback response and reacts with the same speed as the nerve signals would when they travel to the…

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BioMedNewsBreaks – Lineage Cell Therapeutics Inc. (NYSE American: LCTX) (TASE: LCTX) Announces Broadening of Strategic Collaboration Regarding ESI Stem Cell Lines

October 6, 2020 12:49:49

Lineage Cell Therapeutics (NYSE American: LCTX) (TASE: LCTX), a clinical-stage biotechnology company developing novel cell therapies for unmet medical needs, together with its subsidiary ES Cell International Pte Ltd. (“ESI”) and AgeX Therapeutics Inc. (NYSE American: AGE), a company focused on developing and commercializing innovative therapeutics for human aging, recently announced the broadening of their collaborative relationship regarding ESI stem cell lines. According to the update, ESI cell lines are current Good Manufacturing Practice (“cGMP”)-compatible, registered with the National Institutes of Health (“NIH”), and widely studied as a potential source for the industrial-scale manufacture of any cell type in the human body. “Both Lineage and AgeX are pioneering important aspects of regenerative medicine. Working together, we have amended our agreement regarding ESI cell lines derived under cGMP to be optimal for the business needs of each company,” Lineage’s CEO Brian M. Culley said in the press release. “In particular, Lineage has acquired exclusivity for the use of ESI cell lines in spinal cord injury and certain oncology indications. On the other hand, AgeX has gained greater flexibility and independence to support its efforts toward licensing certain technologies and cell lines to third parties. With this step complete, we next intend to explore additional opportunities to collaborate with AgeX on promising tissue regenerating projects.”

To view the full press release, visit https://ibn.fm/9o6yw

About Lineage Cell Therapeutics Inc.

Lineage Cell Therapeutics is a clinical-stage biotechnology company developing novel cell therapies for unmet medical needs. Lineage’s programs are based on its robust proprietary cell-based therapy platform and associated in-house development and manufacturing capabilities. With this platform, Lineage develops and manufactures specialized, terminally differentiated human cells from its pluripotent and progenitor cell-starting materials. These differentiated cells are developed to either replace or support cells that are dysfunctional or absent due to degenerative disease or traumatic injury or administered as a means of helping the body mount an effective immune response to cancer. Lineage’s clinical programs are in markets with billion-dollar opportunities and include three allogeneic (“off-the-shelf”) product candidates: (i) OpRegen(R), a retinal pigment epithelium transplant therapy in Phase 1/2a development for the treatment of dry age-related macular degeneration, a leading cause of blindness in the developed world; (ii) OPC1, an oligodendrocyte progenitor cell therapy in Phase 1/2a development for the treatment of acute spinal cord injuries; and (iii) VAC, an allogeneic dendritic cell therapy platform for immuno-oncology and infectious disease, currently in clinical development for the treatment of non-small cell lung cancer and in preclinical development for additional cancers and as a vaccine against infectious diseases, including SARS-CoV-2, the virus which causes COVID-19. For more information about the company, visit www.LineageCell.com.

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Processa Pharmaceuticals Inc. (NASDAQ: PCSA) is “One to Watch”

October 6, 2020 12:23:46

Processa Pharmaceuticals aims to develop products where existing clinical evidence of efficacy already exists in the targeted unmet medical need condition with the drug itself or a drug with very similar pharmacology
The Processa process focuses on the advancement of drugs that are ready for clinical development or have minimal pre-IND enabling studies to complete
Processa’s current development pipeline features multiple clinical drug candidates, given the recent acquisitions of three additional development-focused licensing agreement since June 2020
In total, the company’s combined scientific, development and regulatory experience has resulted in more than 30 drug approvals by the U.S. Food and Drug Administration

Processa Pharmaceuticals (NASDAQ: PCSA) aims to develop products where existing clinical evidence of efficacy already exists in unmet medical need conditions. In support of this goal, the company has assembled an unparalleled management team, board of directors and product development team featuring experts in developing drug products, from IND-enabling studies to NDA submission. In total, the team’s combined scientific, development and regulatory experience has resulted in more than 30 drug approvals by the U.S. Food and Drug Administration (“FDA”) and more than 100 meetings with the FDA while working on more than 50 drug development programs, including drug products targeted to orphan disease and unmet medical need conditions.

Headquartered in Hanover, Maryland, Processa has built a pipeline of drugs which already have some proof-of-concept clinical data supporting clinical use in…

NOTE TO INVESTORS: The latest news and updates relating to PCSA are available in the company’s newsroom at https://ibn.fm/PCSA

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Georgia Scientists Receive Grant to Improve Mood Disorder Treatment Tool

October 6, 2020 12:21:56

A team of Georgia State scientists has received a two-year grant to further develop a tool to help psychiatrists better diagnose and treat mood disorders. The $875,110 grant was provided by the National Institute of Mental Health and it will fund studies that will make it easier for mental health professionals to quickly diagnose and treat mental health conditions with accuracy. The researchers are based at the Center for the Translational Research in Neuroimaging and Data Science (TReNDS).

TReNDS is a tri-institutional effort supported by Georgia State University, Georgia Institute of Technology, and Emory University that is focused on making better use of complex brain imaging data. The grant was awarded to Advanced Biomedical Informatics Group LLC, a startup led by Jeremy Bockholt. The tool the firm will develop is based on research by Vince Calhoun, Distinguished University Professor of Psychology, and a Georgia Research…

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BioMedNewsBreaks – Predictive Oncology (NASDAQ: POAI) Shareholder Letter Provides Company Update, Status of Subsidiaries

October 6, 2020 11:54:39

Predictive Oncology (NASDAQ: POAI), a knowledge-driven company focused on applying artificial intelligence (“AI”) to personalized medicine and drug discovery, has released a shareholder letter providing a review of where POAI “stands as of today.” The letter noted that, despite a decline of stock price over the past few weeks, the company’s cash burn is stable and even trending down, and revenues are stable and trending upward. The letter notes that POAI has adequate cash for operation, as well as ability to utilize an equity line of credit of more than $10 million. The letter also provides an update on the company’s divisions: Skyline Medical, Helomics, TumorGenesis and Soluble Biotech. The letter notes that Skyline Medical is self-supporting from a cash standpoint. Helomics has launched a restructured clinical test offering to clinicians for ovarian cancer. TumorGenesis will be introducing its Ovarian Cell Line Media at the upcoming BIO-Europe Conference; the media allows researchers to isolate and successfully culture ovarian cancer cells that have previously not been cultured. Soluble Biotech has moved into a new facility that effectively quadruples its office and research space. “As you can see, a lot is happening,” said Predictive Oncology CEO Carl Schwartz in the letter. “Much is occurring under the radar. Much doesn’t make for a press release. However, don’t be discouraged by the lack of ‘blockbuster’ announcements. We are moving forward rapidly, and we expect the fourth quarter to be eventful.”

To view the full press release, visit https://ibn.fm/lbJxa

About Predictive Oncology Inc.

NOTE TO INVESTORS: The latest news and updates relating to POAI are available in the company’s newsroom at http://ibn.fm/POAI

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BioMedNewsBreaks – Genprex Inc. (NASDAQ: GNPX) to Present at Cell and Gene Therapy Sector’s Foremost Annual Conference

October 6, 2020 10:35:06

Genprex (NASDAQ: GNPX), a clinical-stage gene therapy company developing potentially life-changing technologies for cancer and diabetes patients, today announced that it will present at the Alliance for Regenerative Medicine’s (“ARM”) virtual Cell and Gene Meeting on the Mesa, which is set to take place October 12-16, 2020. Genprex’s executive vice president and COO Michael Redman will lead the company’s presentation. The 2020 event will be delivered in a virtual format over the course of five days and feature on-demand company presentations and live-streaming panels. The Cell and Gene Meeting on the Mesa is the sector’s foremost annual conference, bringing together senior executives and top industry decision makers to advance cutting-edge research into cures. Tackling commercialization hurdles currently facing the cell and gene therapy sector, the conference covers a wide range of topics from clinical trial design to alternative, scalable payment models and supply chain platforms for advanced therapies. Interested parties should visit https://ibn.fm/ruXcY for more information or to register for the event.

To view the full press release, visit https://ibn.fm/kX4bh

About Genprex Inc.

NOTE TO INVESTORS: The latest news and updates relating to GNPX are available in the company’s newsroom at http://ibn.fm/GNPX

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CNS Pharmaceuticals Inc. (NASDAQ: CNSP) Partnership with Imaging Specialists IAG Gives Tech Boost to Upcoming Brain Cancer Drug Trials

October 5, 2020 12:12:01

Clinical-stage biotech developer CNS Pharmaceuticals is working to demonstrate the potential effectiveness of its novel drug, Berubicin, in treating aggressive and rare brain cancer glioblastoma multiforme (“GBM”)
CNS expects to launch Phase II trials of Berubicin later this year or in Q1 of 2021, building on promising results shown in initial trials
One patient in the Phase I trial has remained cancer-free over the course of 14 years, and 44 percent of the patients who could be evaluated experienced a clinically significant positive response to Berubicin
CNS’s laser-focused strategy for developing a GBM therapy is also leading the company to prepare, through its sub-licensee partner WPD Pharmaceuticals, for a first-ever Phase I pediatric trial of Berubicin in Poland as well as continuing the development of the company’s second drug candidate, WP1244, which has shown tremendous promise in stopping cancer proliferation in preclinical studies comparing it to chemotherapy drug daunorubicin

CNS Pharmaceuticals (NASDAQ: CNSP) is building its technologically advanced strategy for demonstrating the potential brain tumor-fighting capabilities of its novel drug Berubicin, announcing recently an agreement with medical imaging company Image Analysis Group (“IAG”) to evaluate upcoming clinical phase II patient trial scansin real time.

IAG’s proprietary platform DYNAMIKA is an AI-driven technology developed to aid in the analysis of patient responses during pharmaceutical trial’s, and IAG has extensive experience in partnering with the biotech industry — oncology companies in particular — to provide a centralized reading of…

NOTE TO INVESTORS: The latest news and updates relating to CNSP are available in the company’s newsroom at https://ibn.fm/CNSP

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Laser-Welded Sugar: The New Technique to Repair Damaged Blood Vessels?

October 5, 2020 11:05:19

A study that was published in the Nature Biomedical Engineering journal by Rice University bioengineers demonstrated how the researchers created blood vessel networks from 3D-printed sugar templates which they used to keep tightly packed cells alive for a 2-week period.

Ian Kinstlinger, who is the lead author of the study, said that among the biggest obstacles in developing clinically significant tissues was trying to provide…

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BioMedNewsBreaks – LexaGene Holdings, Inc. (TSX.V: LXG) (OTCQB: LXXGF) Issues Corporate Update

October 5, 2020 10:49:55

LexaGene Holdings (TSX.V: LXG) (OTCQB: LXXGF), a molecular diagnostics company that develops fully automated rapid pathogen detection systems, today provided a general corporate update. Among highlights provided in the update, LexaGene is in a strong position to support its development goals for the next year and beyond with its treasury currently standing at US$11.3 million (C$14.9 million). “Our MiQLab(TM) pathogen detection system has 230 unique components. Over the summer, the coronavirus pandemic caused some supply chain issues for several key components that delayed the manufacturing, optimization and testing of these systems. Just recently, these supply chain issues were resolved and we are now testing and optimizing our MiQLabs,” LexaGene’s founder and CEO Dr. Jack Regan said in the news release. “To support our sales efforts, I’m pleased to announce we have started an Early Access Program for key opinion leaders in veterinary and open-access markets. I expect we will be shipping our first unit(s) for this program by mid-Q4 of this year.”

To view the full press release, visit https://ibn.fm/I8fJR

About LexaGene Holdings Inc.

LexaGene is a molecular diagnostics company that develops molecular diagnostic systems for pathogen detection and genetic testing for other molecular markers for on-site rapid testing in veterinary diagnostics, food safety and for use in open-access markets, such as clinical research, agricultural testing and biodefense. End-users simply need to collect a sample, load it onto the instrument with a sample preparation cartridge, enter sample ID and press “go.” The MiQLab(TM) system delivers excellent sensitivity, specificity and breadth of detection and can return results in approximately one hour. The unique open-access feature is designed for custom testing so that end-users can load their own real-time PCR assays onto the instrument to target any genetic target of interest. For more information, visit the company’s website at www.LexaGene.com.

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Some Cerebral Palsy Cases Could Be Due to a Patient’s Genes, Research Finds

October 5, 2020 08:45:48

In an article that was published in Nature Genetics, scientists have confirmed that almost 14% of all cerebral palsy cases may be connected to an individual’s genes and indicate that those genes control how brain circuits are wired in early development. Cerebral palsy is a brain disorder that affects an individual’s ability to move and maintain posture and balance. It’s a motor disability that is common in childhood.

The National Institute of Neurological Disorders was the main funder behind this research. The scientists’ findings were based on the biggest genetic study of cerebral palsy that has ever been conducted. Additionally, the conclusion also shed light on the importance of understanding…

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New Study Confirms Children Are Significantly Less Likely to Contract Coronavirus

October 2, 2020 12:41:54

A new study that centered on global coronavirus transmission data discovered that young people and children are about 40% less likely to be infected with COVID-19 as compared to adults when exposed to an individual who has the virus.

The study, which was co-led by researchers from University College London and published in JAMA Pediatrics, added more than 13,900 studies to its May pre-print in order to update their meta-analysis and systematic review. The additional studies were used to understand how susceptible children were to the coronavirus and whether they transmitted…

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BioMedNewsBreaks – Predictive Oncology Inc.’s (NASDAQ: POAI) Helomics CIO Discusses Convergence of AI, Data and Biology on DojoLIVE!

October 2, 2020 12:09:46

Predictive Oncology (NASDAQ: POAI), a knowledge-driven company focused on applying artificial intelligence (“AI”) to personalized medicine and drug discovery, was featured in a recent article discussing the appearance of one of its executives, Helomics CIO Mark Collins, PhD, on DojoLIVE! (https://ibn.fm/Y9fBZ). POAI’s Helomics subsidiary applies AI to its rich data gathered from more than 150,000 tumors in an effort to personalize cancer therapies and drive the development of new targeted therapies in collaborations with pharmaceutical companies. Collins addressed this powerful work and his longtime passion during the interview titled, “Can We Cure Cancer with Artificial Intelligence?” “The last 20 years of my career, I’ve been trying to realize that vision of how the convergence of AI, data and biology can be used to discover new drugs,” he said, noting that Helomics holds a massive collection of data and AI capabilities. “And it’s that convergence of AI, the big data, if you will, and the biology, where we’re able to test drugs on living tumor tissue rather than some artificial system, that we really believe will revolutionize drug discovery and impact the patients of tomorrow.”

To view the full article, visit https://ibn.fm/nsI4N

About Predictive Oncology Inc.

NOTE TO INVESTORS: The latest news and updates relating to POAI are available in the company’s newsroom at http://ibn.fm/POAI

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BioMedNewsBreaks – 180 Life Sciences Corp. Setting the Stage for Success in Bringing Novel Products to Market

October 2, 2020 11:48:14

180 Life Sciences, a clinical-stage biotechnology company, is focused on research to solve one of the world’s most significant drivers of disease – inflammation. The company currently has three programs for the development of novel drugs in the areas of fibrosis and anti-TNF, inflammatory pain and ulcerative colitis in ex-smokers. A recent article discusses the company’s strategy to expedite the path to market. The piece reads, “180 Life Sciences has mitigated the risks of its drug development through multiple programs at various stages of development. The company is actively decreasing costs and expediting the time to market by using grant funding and cost-effective trials internationally. Additionally, it has recruited teams with backgrounds in excellence, setting up the stage for success.”

To view the full article, visit https://ibn.fm/9aRuw

About 180 Life Sciences Corp.

180 Life Sciences is a clinical-stage biotechnology company focused on the development of novel drugs that fulfill unmet needs in inflammatory diseases, fibrosis and pain by leveraging the combined expertise of luminaries in therapeutics from Oxford University, the Hebrew University and Stanford University. KBL Merger Corp. IV (NASDAQ: KBLM) previously announced plans to merge with 180 Life Sciences and, in connection with the merger, consummated a bridge financing on June 29, 2020, and submitted its latest S4 filing with the SEC on August 28, 2020. Close of the business combination is expected in the fourth quarter of 2020. Following the merger, the new company will be listed on the Nasdaq Capital Market under ticker symbol “ATNF.” For more information, visit the company’s website at www.180LifeSciences.com.

KBLM has valued 180 Life Sciences at $175 million, with the acquisition being carried out via a share swap, with each share of 180 Life Sciences to be exchanged for one share of KBLM.

NOTE TO INVESTORS: The latest news and updates relating to 180 Life Sciences are available in the company’s newsroom at http://ibn.fm/180

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VistaGen Therapeutics Inc. (NASDAQ: VTGN) is “One to Watch”

October 2, 2020 09:48:46

VistaGen’s product portfolio consists of three novel drug candidates that, together, target multiple anxiety disorders, depression disorders and neurological disorders
Two of the company’s drug candidates have received an FDA fast track designation, including for the treatment of social anxiety disorder, major depressive disorder and neuropathic pain.
The global CNS therapeutics market is estimated to reach $130 billion by 2025
The two most common mental health conditions – anxiety and depression – cost the global economy an estimated $1 trillion each year
VistaGen is committed to developing and commercializing multiple new generation medications that go beyond the standard of care in large markets for treatment of anxiety, depression and other central nervous system (“CNS”) disorders, potentially addressing the unmet needs of millions worldwide
The company’s efforts are advanced by a skilled management team with decades of experience in biotechnology, pharmaceuticals, CNS drug development and more

The company is headquartered in South San Francisco, California, the “Birthplace of Biotechnology,” among the largest cluster of biotechnology companies in…

NOTE TO INVESTORS: The latest news and updates relating to VTGN are available in the company’s newsroom at https://ibn.fm/VTGN

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High Fructose Intake May Worsen Inflammatory Bowel Disease