According to a systematic review that was reported in Therapeutic Advances in Psychopharmacology, psychedelic drugs such as LSD and mescaline decrease the recognition of negative facial expressions. Generally, the main facial expressions characterizing basic human emotions are happiness, sadness, surprise, disgust, fear and anger. The psychedelic substances do this by adjusting the amygdala’s activity, which is the region of the brain that drives a person’s flight or fight response.
A postdoctoral fellow at the University of Sao Paulo, Rafael Guimarães dos Santos, who is the study’s author, explained that they’d been looking into the effects of ayahuasca on humans for the past decade and a half. They discovered that its effects, as well as those of other serotonergic hallucinogens like psilocybin and LSD, involve…
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