Tango Therapeutics Inc. (NASDAQ: TNGX), a Boston-based precision oncology company developing therapies targeting synthetic lethality in cancer, reported short interest of approximately 45.82 million shares as of Jan. 30, 2026—equal to about 39.45% of its public float and up from the prior reporting period. With shares trading in the $12.90 to $12.97 range in mid-February and a market capitalization near $1.74 billion, the company reflects one of the higher short-interest profiles within the mid-cap biotech space.
Days to cover range from roughly 14 to 17 depending on the source, underscoring the scale of bearish positioning. In development-stage biotechnology companies where valuations are often sensitive to clinical updates and broader sector conditions, short exposure at these levels can contribute to amplified price volatility during periods of market uncertainty.
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