VistaGen Therapeutics (NASDAQ: VTGN), a biopharmaceutical company developing new generation medicines for anxiety, depression and other central nervous system (“CNS”) disorders, was featured in an Equity Research Company Update by Maxim Group LLC. The report, titled “Benzo-Benefits Without the Benzo-Baggage – The Case for PH94B Builds,” highlights potential benefits of VistaGen’s PH94B drug candidate, a nasal spray designed for treatment of adults with social anxiety disorder, as compared to treatment with benzodiazepines. The report reads, “Benzodiazepines (benzos) have been available to treat anxiety since the 1960s, and include well-known products such as Xanax, Ativan, and Klonopin. These drug compounds work by binding to the receptors located on GABA (gamma-aminobutyric acid), the main inhibitory neurotransmitter in the brain. Although benzos produce anxiolytic effects, they are highly addictive and come with a host of side effects (sedation, impaired cognition, etc). Essentially, anywhere there is GABA, a benzo will have an impact and that’s an issue. PH94B is a neuroactive steroid called a pherine, which also activates GABA neurotransmission, but only in the central amygdala and not throughout the entire brain and central nervous system. Through its nasal spray formulation, a small amount of PH94B is delivered locally to cells in the nasal passages to activate chemosensory neurons that trigger neural circuits in the brain which suppress fear and anxiety. The drug itself never enters the brain, a key differentiator.”
To view the full report, visit https://ibn.fm/eOwEf
About VistaGen Therapeutics
VistaGen is a clinical-stage biopharmaceutical company developing new generation medicines for anxiety, depression and other CNS disorders where the current standard of care is inadequate, resulting in high unmet need. Each of VistaGen’s three drug candidates has a differentiated mechanism of action, an exceptional safety profile in all studies to date, and therapeutic potential in multiple CNS markets. For more information, please visit www.VistaGen.com.
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