Everything You Need to Know About Nonreactive Hep B Screening Results

October 16, 2023 13:46:33

An estimated 1.2 million people in the United States. and 350 million globally are infected with hepatitis B, a type of viral infection that attacks the liver. The condition is often characterized by symptoms such as dark urine, fever, appetite loss, abdominal pain, fatigue and weakness, jaundice and joint pain.

Around 1% of hepatitis patients will develop fulminant hepatitis, a dangerous condition that can lead to liver failure and death while 5% of patients who develop hepatitis B in adulthood will develop chronic hepatitis B. However, the majority of hepatitis B patients can manage the condition through pharmaceuticals, eating a healthy diet and drinking fluids to remain hydrated.

Early diagnosis through testing is key to addressing the condition before symptoms can snowball and become more severe. Physicians typically test for the condition using a hepatitis B surface antibody test (HBsAB) to check for blood antibodies and determine if an individual has developed immunity to the hepatitis B virus (HBV). Taking a BBsAb test will allow you to detect whether you have HBV immunity and if you currently have antibodies that can stave off infections in the future. This test can also help physicians determine if you were recently exposed to HBV and how recently the exposure occurred.

Physicians will deploy either the hepatitis B core antibody (HBcAb) test or the hepatitis B surface antigen (HBsAg) test to check for current or previous infections. HBcAB tests can detect both previous and current infections while HBsA tests can only detect current infections. Both tests will provide either reactive (positive) or nonreactive (negative) results.

A reactive HBsAb result indicates that you were previously infected with hepatitis B or vaccinated and now have immunity to HBV while a nonreactive HbsAB result typically indicates that you have no immunity to HBV.

Doctors can also interpret nonreactive results from both tests in various ways. For instance, physicians may recommend that a patient who had three negative results take a hepatitis B vaccine because they likely aren’t immune to the condition.

Patients who receive reactive HbsAg and HBcAb tests and nonreactive (negative) HBsAb tests may be diagnosed with chronic or acute hepatitis B. Your doctor may recommend further tests to ascertain whether you have acute hepatitis B in this case.

Inversely, positive HBcAb results coupled with negative HBsAg and HBsAg tests may indicate a previous hepatitis B infection, an uncommon HBsAg strain that slipped under the lab’s radar, or a false positive. Nonreactive HBsAb test results coupled with reactive HBsAg and HBcAb test results may also call for further testing.

Entities such as Renovaro BioSciences Inc. (NASDAQ: RENB) are actively developing treatments that they hope will be able to cure hepatitis B as well as other serious infectious diseases that are threatening populations around the globe.

NOTE TO INVESTORS: The latest news and updates relating to Renovaro BioSciences Inc. (NASDAQ: RENB) are available in the company’s newsroom at https://ibn.fm/RENB

About BioMedWire

BioMedWire (“BMW”) is a specialized communications platform with a focus on the latest developments in the Biotechnology (BioTech), Biomedical Sciences (BioMed)and Life Sciences sectors. It is one of 60+ brands within the Dynamic Brand Portfolio @ IBN that delivers: (1) access to a vast network of wire solutions via InvestorWire to efficiently and effectively reach a myriad of target markets, demographics and diverse industries; (2) article and editorial syndication to 5,000+ outlets; (3) enhanced press release enhancement to ensure maximum impact; (4) social media distribution via IBN to millions of social media followers; and (5) a full array of tailored corporate communications solutions. With broad reach and a seasoned team of contributing journalists and writers, BMW is uniquely positioned to best serve private and public companies that want to reach a wide audience of investors, influencers, consumers, journalists and the general public. By cutting through the overload of information in today’s market, BMW brings its clients unparalleled recognition and brand awareness.

BMW is where breaking news, insightful content and actionable information converge.

To receive SMS alerts from BioMedWire, “Biotech” to 844-397-5787 (U.S. Mobile Phones Only)

For more information, please visit https://www.BioMedWire.com

Please see full terms of use and disclaimers on the BioMedWire website applicable to all content provided by BMW, wherever published or re-published: https://www.BioMedWire.com/Disclaimer

San Francisco, CA
415.949.5050 Office

BioMedWire is powered by IBN