Nader Z. Pourhassan, Ph.D., the president and CEO of CytoDyn (OTCQB: CYDY), was recently interviewed by TWST.com. The interview was highlighted in a recent article titled, “CytoDyn About to Take Off? CEO Nader Pourhassan Ph. D. Says Yes,” which provided an overview of the biotechnology company from the perspective of its president & CEO. Dr. Pourhassan discussed the rapid clinical development of PRO 140 which is being developed as a therapy for HIV. He has overseen PRO 140 from its acquisition to phase II development and phase III trials. In addition, Dr. Pourhassan has been involved in the preclinical and clinical development of PRO 140 in other immunological indications and cancer. “In regard to monotherapy, PRO 140 could allow patients to put away all their pills. We have a small group of patients right now who have gone four years without pills with PRO 140 as a monotherapy. It takes between 30 seconds and two minutes once a week to subcutaneously self-inject themselves at home, and that is all they need,” CytoDyn president and CEO Nader Z. Pourhassan, Ph.D. stated in the interview.
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CytoDyn is a biotechnology company developing innovative treatments for multiple therapeutic indications based on PRO 140 (leronlimab), a novel humanized monoclonal antibody targeting the CCR5 receptor. CCR5 plays a key role in the ability of HIV to enter and infect healthy T-cells. The CCR5 receptor is also implicated in tumor metastasis and in immune-mediated illnesses such as graft-vs-host disease (GvHD) and NASH. CytoDyn has successfully completed a Phase 3 pivotal trial with PRO 140 in combination with standard anti-retroviral therapies in HIV-infected treatment-experienced patients. The Company plans to seek FDA approval for PRO 140 in combination therapy and plans to complete the filing of a Biological License Application (BLA) in the first quarter of 2019 for that indication. CytoDyn is also conducting a Phase 3 investigative trial with PRO 140 as a once-weekly monotherapy for HIV-infected patients, and plans to initiate a registration-directed study of PRO 140 monotherapy indication, which if successful, could support a label extension. Clinical results to date from multiple trials have shown that PRO 140 can significantly reduce viral burden in people infected with HIV with no reported drug-related serious adverse events (SAEs). Moreover, results from a Phase 2b clinical trial demonstrated that PRO 140 monotherapy can prevent viral escape in HIV-infected patients, with some patients on PRO 140 monotherapy remaining virally suppressed for more than four years. CytoDyn is also conducting a Phase 2 trial to evaluate PRO 140 for the prevention of GvHD and expects to initiate clinical trials with PRO 140 in metastatic triple-negative breast cancer in 2018. For more information, visit the company’s website at www.CytoDyn.com
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