BriaCell Therapeutics Corp. (OTCQB: BCTXF) (TSX.V: BCT) recently initiated patient dosing in a combination study of lead clinical candidate Bria-IMT with Merck’s (NYSE: MRK) KEYTRUDA® and Bristol-Myers’ (NYSE: BMY) YERVOY®. A recent proof of concept study of Bria-IMT indicated excellent targeted anti-tumor activity and outstanding safety and tolerability in advanced breast cancer patients. An article further discussing the company reads, “BriaCell continues its commitment to exploring new methods of addressing the advanced breast cancer community’s unmet medical needs, and the company is eager to test this novel combination treatment approach and believes that it will offer significant clinical benefits to patients who have advanced breast cancer.”
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BriaCell is an immuno-oncology focused biotechnology company developing targeted and safe approaches for the management of cancer. BriaCell is currently conducting a Phase I/IIa clinical trial of Bria-IMT, its lead candidate, in a combination study with pembrolizumab [Keytruda; manufactured by Merck & Co., Inc.] or ipilimumab [Yervoy; manufactured by Bristol-Myers Squibb Company]. The combination study is listed in ClinicalTrials.gov as NCT03328026. BriaCell is developing Bria-OTS, an off-the-shelf personalized immunotherapy, for advanced breast cancer. Bria-OTS immunotherapy treatments are personalized to match the patient without the need for personalized manufacturing. Bria-OTS, which is expected to cover over 90 percent of the patient population, is designed to produce a potent and selective immune response against the cancer of each patient while eliminating the time, expense, and complex manufacturing logistics associated with other personalized immunotherapies. For more information, visit the company’s website at www.BriaCell.com.
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